Odor discrimination deficits in schizophrenia: Association with eye movement dysfunction

D. Malaspina; A. D. Wray; J. H. Friedman; X. Amador; S. Yale; A. Hasan; J. M. Gorman; C. A. Kaufmann

doi:10.1176/jnp.6.3.273

Odor discrimination deficits in schizophrenia: Association with eye movement dysfunction

D. Malaspina, A. D. Wray, J. H. Friedman, X. Amador, S. Yale, A. Hasan, J. M. Gorman, C. A. Kaufmann

Research output: Contribution to journal › Article › peer-review

62 Scopus citations

Abstract

Odor discrimination deficits were found in 80% of 20 schizophrenia patients and in none of the 20 age- and sex-matched comparison subjects. Olfactory discrimination was reliably measured in the patients. Twelve patients in this study also had smooth pursuit eye movement (SPEM) qualitatively recorded. The olfactory discrimination scores were highly correlated to SPEM but not to other clinical measures. This correlation suggests a shared neurobiology, possibly involving working memory.

Original language	English
Pages (from-to)	273-278
Number of pages	6
Journal	Journal of Neuropsychiatry and Clinical Neurosciences
Volume	6
Issue number	3
DOIs	https://doi.org/10.1176/jnp.6.3.273
State	Published - 1994
Externally published	Yes

Access to Document

10.1176/jnp.6.3.273

Cite this

@article{31e618ad0c2042c58e3e5ebaef9f3e18,

title = "Odor discrimination deficits in schizophrenia: Association with eye movement dysfunction",

abstract = "Odor discrimination deficits were found in 80% of 20 schizophrenia patients and in none of the 20 age- and sex-matched comparison subjects. Olfactory discrimination was reliably measured in the patients. Twelve patients in this study also had smooth pursuit eye movement (SPEM) qualitatively recorded. The olfactory discrimination scores were highly correlated to SPEM but not to other clinical measures. This correlation suggests a shared neurobiology, possibly involving working memory.",

author = "D. Malaspina and Wray, {A. D.} and Friedman, {J. H.} and X. Amador and S. Yale and A. Hasan and Gorman, {J. M.} and Kaufmann, {C. A.}",

year = "1994",

doi = "10.1176/jnp.6.3.273",

language = "English",

volume = "6",

pages = "273--278",

journal = "Journal of Neuropsychiatry and Clinical Neurosciences",

issn = "0895-0172",

publisher = "American Psychiatric Association",

number = "3",

}

TY - JOUR

T1 - Odor discrimination deficits in schizophrenia

T2 - Association with eye movement dysfunction

AU - Malaspina, D.

AU - Wray, A. D.

AU - Friedman, J. H.

AU - Amador, X.

AU - Yale, S.

AU - Hasan, A.

AU - Gorman, J. M.

AU - Kaufmann, C. A.

PY - 1994

Y1 - 1994

N2 - Odor discrimination deficits were found in 80% of 20 schizophrenia patients and in none of the 20 age- and sex-matched comparison subjects. Olfactory discrimination was reliably measured in the patients. Twelve patients in this study also had smooth pursuit eye movement (SPEM) qualitatively recorded. The olfactory discrimination scores were highly correlated to SPEM but not to other clinical measures. This correlation suggests a shared neurobiology, possibly involving working memory.

AB - Odor discrimination deficits were found in 80% of 20 schizophrenia patients and in none of the 20 age- and sex-matched comparison subjects. Olfactory discrimination was reliably measured in the patients. Twelve patients in this study also had smooth pursuit eye movement (SPEM) qualitatively recorded. The olfactory discrimination scores were highly correlated to SPEM but not to other clinical measures. This correlation suggests a shared neurobiology, possibly involving working memory.

UR - http://www.scopus.com/inward/record.url?scp=0028095546&partnerID=8YFLogxK

U2 - 10.1176/jnp.6.3.273

DO - 10.1176/jnp.6.3.273

M3 - Article

C2 - 7950351

AN - SCOPUS:0028095546

SN - 0895-0172

VL - 6

SP - 273

EP - 278

JO - Journal of Neuropsychiatry and Clinical Neurosciences

JF - Journal of Neuropsychiatry and Clinical Neurosciences

IS - 3

ER -

Odor discrimination deficits in schizophrenia: Association with eye movement dysfunction

Abstract

Access to Document

Fingerprint

Cite this