Oculomotor corollary discharge signaling is related to repetitive behavior in children with autism spectrum disorder

Beier Yao; Martin Rolfs; Christopher McLaughlin; Emily L. Isenstein; Sylvia B. Guillory; Hannah Grosman; Deborah A. Kashy; Jennifer H. Foss-Feig; Katharine N. Thakkar

doi:10.1167/jov.21.8.9

Oculomotor corollary discharge signaling is related to repetitive behavior in children with autism spectrum disorder

Beier Yao, Martin Rolfs, Christopher McLaughlin, Emily L. Isenstein, Sylvia B. Guillory, Hannah Grosman, Deborah A. Kashy, Jennifer H. Foss-Feig, Katharine N. Thakkar

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Corollary discharge (CD) signals are “copies” of motor signals sent to sensory regions that allow animals to adjust sensory consequences of self-generated actions. Autism spectrum disorder (ASD) is characterized by sensory and motor deficits, which may be underpinned by altered CD signaling. We evaluated oculomotor CD using the blanking task, which measures the influence of saccades on visual perception, in 30 children with ASD and 35 typically developing (TD) children. Participants were instructed to make a saccade to a visual target. Upon saccade initiation, the presaccadic target disappeared and reappeared to the left or right of the original position.

Original language	English
Pages (from-to)	1-20
Number of pages	20
Journal	Journal of Vision
Volume	21
Issue number	8
DOIs	https://doi.org/10.1167/jov.21.8.9
State	Published - Aug 2021

Keywords

efference copy
remapping
saccadic eye movements
sensory hyporesponsiveness
trans-saccadic perception

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10.1167/jov.21.8.9

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title = "Oculomotor corollary discharge signaling is related to repetitive behavior in children with autism spectrum disorder",

abstract = "Corollary discharge (CD) signals are “copies” of motor signals sent to sensory regions that allow animals to adjust sensory consequences of self-generated actions. Autism spectrum disorder (ASD) is characterized by sensory and motor deficits, which may be underpinned by altered CD signaling. We evaluated oculomotor CD using the blanking task, which measures the influence of saccades on visual perception, in 30 children with ASD and 35 typically developing (TD) children. Participants were instructed to make a saccade to a visual target. Upon saccade initiation, the presaccadic target disappeared and reappeared to the left or right of the original position.",

keywords = "efference copy, remapping, saccadic eye movements, sensory hyporesponsiveness, trans-saccadic perception",

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AU - Grosman, Hannah

AU - Kashy, Deborah A.

AU - Foss-Feig, Jennifer H.

AU - Thakkar, Katharine N.

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Oculomotor corollary discharge signaling is related to repetitive behavior in children with autism spectrum disorder

Abstract

Keywords

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