Oculomotor corollary discharge signaling is related to repetitive behavior in children with autism spectrum disorder

Beier Yao, Martin Rolfs, Christopher McLaughlin, Emily L. Isenstein, Sylvia B. Guillory, Hannah Grosman, Deborah A. Kashy, Jennifer H. Foss-Feig, Katharine N. Thakkar

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Corollary discharge (CD) signals are “copies” of motor signals sent to sensory regions that allow animals to adjust sensory consequences of self-generated actions. Autism spectrum disorder (ASD) is characterized by sensory and motor deficits, which may be underpinned by altered CD signaling. We evaluated oculomotor CD using the blanking task, which measures the influence of saccades on visual perception, in 30 children with ASD and 35 typically developing (TD) children. Participants were instructed to make a saccade to a visual target. Upon saccade initiation, the presaccadic target disappeared and reappeared to the left or right of the original position.

Original languageEnglish
Pages (from-to)1-20
Number of pages20
JournalJournal of Vision
Volume21
Issue number8
DOIs
StatePublished - Aug 2021

Keywords

  • efference copy
  • remapping
  • saccadic eye movements
  • sensory hyporesponsiveness
  • trans-saccadic perception

Fingerprint

Dive into the research topics of 'Oculomotor corollary discharge signaling is related to repetitive behavior in children with autism spectrum disorder'. Together they form a unique fingerprint.

Cite this