TY - JOUR
T1 - Ocular involvement in chronic sarcoidosis
AU - Jabs, Douglas A.
AU - Johns, Carol J.
N1 - Funding Information:
From the Wilmer Ophthalmological Institute, Departments of Ophthalmology (Dr. Jabs) and Medicine (Dr. Johns), Johns Hopkins University School of Medicine, Baltimore, Maryland. This study was supported in part by grant EY 01765 from the National Institutes of Health. This study was presented in part at the meeting of the Association for Research in Vision and Ophthalmology, Sarasota, Florida, April 29, 1986.
PY - 1986/9/15
Y1 - 1986/9/15
N2 - Although spontaneous remissions often occur in sarcoidosis, chronic persistent disabling disease is also observed. Of a series of 183 patients with chronic sarcoidosis, 47 (26%) had ophthalmic involvement. In this series, chronic sarcoid was defined as disease for a minimum of five years. Patients were followed primarily for their systemic disease for a mean of 13 years. Uveitis developed in 35 patients (19%) and was an early manifestation in 32 (91%). The course of the ocular disease did not necessarily parallel that of the systemic disease. Despite the chronic nature of the underlying disease, the anterior uveitis did not pursue a chronic course in 15 of 33 patients (45%) and was generally characterized by a single episode at the onset of disease. Chronic uveitis and secondary glaucoma were poor prognostic signs, as eight of 11 patients with uveitis and glaucoma suffered severe visual loss.
AB - Although spontaneous remissions often occur in sarcoidosis, chronic persistent disabling disease is also observed. Of a series of 183 patients with chronic sarcoidosis, 47 (26%) had ophthalmic involvement. In this series, chronic sarcoid was defined as disease for a minimum of five years. Patients were followed primarily for their systemic disease for a mean of 13 years. Uveitis developed in 35 patients (19%) and was an early manifestation in 32 (91%). The course of the ocular disease did not necessarily parallel that of the systemic disease. Despite the chronic nature of the underlying disease, the anterior uveitis did not pursue a chronic course in 15 of 33 patients (45%) and was generally characterized by a single episode at the onset of disease. Chronic uveitis and secondary glaucoma were poor prognostic signs, as eight of 11 patients with uveitis and glaucoma suffered severe visual loss.
UR - http://www.scopus.com/inward/record.url?scp=0022515066&partnerID=8YFLogxK
U2 - 10.1016/0002-9394(86)90001-2
DO - 10.1016/0002-9394(86)90001-2
M3 - Article
C2 - 3752193
AN - SCOPUS:0022515066
SN - 0002-9394
VL - 102
SP - 297
EP - 301
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
IS - 3
ER -