Occupational lower airway disease in relation to World Trade Center inhalation exposure

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19 Scopus citations


Purpose of Review: To summarize the knowledge about the occupational lower airway diseases that seem related to exposures at the World Trade Center disaster site. Recent Findings: Those diseases have been characterized as irritant-induced asthma, chronic nonspecific bronchitis, chronic bronchiolitis/small airway disease, and aggravated preexistent chronic obstructive lung disease (most frequently chronic obstructive pulmonary disease, but also asthma), with the expected overlapping features among them. One remarkable characteristic of the irritant-induced asthma observed among these workers was the slow onset of symptoms and long delay in clinical diagnoses. Summary: Longitudinal studies suggest that both the incidence and the associated functional decline of these predominantly obstructive lung diseases stabilized several years ago, but longer follow-up is clearly necessary.

Original languageEnglish
Pages (from-to)97-102
Number of pages6
JournalCurrent Opinion in Allergy and Clinical Immunology
Issue number2
StatePublished - Apr 2011


  • Airway diseases
  • asthma
  • bronchial hyperreactivity
  • bronchiolitis
  • chronic obstructive pulmonary disease
  • inhalation injury
  • irritants
  • lung diseases
  • occupational diseases
  • toxic inhalation


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