TY - JOUR
T1 - Occult Pseudoxanthoma Elasticum in Patients with Premature Cardiovascular Disease
AU - Lebwohl, Mark
AU - Halperin, Jonathan
AU - Phelps, Robert G.
PY - 1993/10/21
Y1 - 1993/10/21
N2 - Pseudoxanthoma elasticum is an inherited disorder of connective tissue that is associated with numerous systemic manifestations, including premature coronary artery disease. Without a serologic marker, the diagnosis relies on clinical features and the histologic demonstration of abnormal, calcified elastic fibers1,2. The typical patient presents with yellow macules or papules that can become confluent to form plaques and, in severe cases, redundant folds of skin. Cutaneous lesions have been likened to “plucked chicken skin.” In patients whose skin is mildly affected, the condition may be difficult to recognize. Ocular complications occasionally occur without the characteristic skin lesions. The histologic…
AB - Pseudoxanthoma elasticum is an inherited disorder of connective tissue that is associated with numerous systemic manifestations, including premature coronary artery disease. Without a serologic marker, the diagnosis relies on clinical features and the histologic demonstration of abnormal, calcified elastic fibers1,2. The typical patient presents with yellow macules or papules that can become confluent to form plaques and, in severe cases, redundant folds of skin. Cutaneous lesions have been likened to “plucked chicken skin.” In patients whose skin is mildly affected, the condition may be difficult to recognize. Ocular complications occasionally occur without the characteristic skin lesions. The histologic…
UR - http://www.scopus.com/inward/record.url?scp=0027504594&partnerID=8YFLogxK
U2 - 10.1056/NEJM199310213291705
DO - 10.1056/NEJM199310213291705
M3 - Article
C2 - 8413390
AN - SCOPUS:0027504594
SN - 0028-4793
VL - 329
SP - 1237
EP - 1239
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 17
ER -