Nurse-led disease management for hypertension control in a diverse urban community: A randomized trial

Paul L. Hebert, Jane E. Sisk, Leah Tuzzio, Jodi M. Casabianca, Velvie A. Pogue, Jason J. Wang, Yingchun Chen, Christine Cowles, Mary Ann McLaughlin

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44 Scopus citations


Background: Treated but uncontrolled hypertension is highly prevalent in African American and Hispanic communities. Objective: To test the effectiveness on blood pressure of home blood pressure monitors alone or in combination with follow-up by a nurse manager. Design: Randomized controlled effectiveness trial. Patients: Four hundred and sixteen African American or Hispanic patients with a history of uncontrolled hypertension. Patients with blood pressure 150/95, or 140/85 for patients with diabetes or renal disease, at enrollment were recruited from one community clinic and four hospital outpatient clinics in East and Central Harlem, New York City. Intervention: Patients were randomized to receive usual care or a home blood pressure monitor plus one in-person counseling session and 9 months of telephone follow-up with a registered nurse. During the trial, the home monitor alone arm was added. Main Measures: Change in systolic and diastolic blood pressure at 9 and 18 months. Key Results: Changes from baseline to 9 months in systolic blood pressure relative to usual care was -7.0 mm Hg (Confidence Interval [CI], -13.4 to -0.6) in the nurse management plus home blood pressure monitor arm, and +1.1 mm Hg (95% CI, -5.5 to 7.8) in the home blood pressure monitor only arm. No statistically significant differences in systolic blood pressure were observed among treatment arms at 18 months. No statistically significant improvements in diastolic blood pressure were found across treatment arms at 9 or 18 months. Changes in prescribing practices did not explain the decrease in blood pressure in the nurse management arm. Conclusions: A nurse management intervention combining an in-person visit, periodic phone calls, and home blood pressure monitoring over 9 months was associated with a statistically significant reduction in systolic, but not diastolic, blood pressure compared to usual care in a high risk population. Home blood pressure monitoring alone was no more effective than usual care.

Original languageEnglish
Pages (from-to)630-639
Number of pages10
JournalJournal of General Internal Medicine
Issue number6
StatePublished - Jun 2012


  • home blood pressure monitor
  • hypertension
  • minority
  • nurse management
  • randomized trial


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