Noninvasive Technologies for the Diagnosis of Cutaneous Melanoma

Richard R. Winkelmann, Aaron S. Farberg, Alex M. Glazer, Darrell S. Rigel

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations

Abstract

Multispectral analysis devices assess pigmented lesion disorganization at different levels using variable wavelengths of light. Computerized algorithms measure morphologic disorganization of the pigmented skin lesion. Aggregated data of 855 participants investigating the influence of multispectral digital skin lesion analysis (MSDSLA) on practitioner decisions to biopsy pigmented skin lesions revealed the overall sensitivity for detection of melanoma improved from 70% to 88%. Participant specificity increased from 52% to 58% after MSDSLA. Five studies using spectrophotometric intracutaneous analysis scope to evaluate suspicious pigmented skin lesions demonstrated an overall sensitivity and specificity of 85% and 81%, respectively, for the detection of melanoma.

Original languageEnglish
Pages (from-to)453-456
Number of pages4
JournalDermatologic Clinics
Volume35
Issue number4
DOIs
StatePublished - Oct 2017
Externally publishedYes

Keywords

  • Diagnosis
  • Medical device
  • Melanoma
  • Multispectral analysis
  • Noninvasive
  • Technology

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