Cardiovascular disease is one of the leading causes of mortality and morbidity worldwide. Atherosclerosis imaging has traditionally focused on detection of obstructive luminal stenoses or measurements of plaque burden. However, with advances in imaging technology it has now become possible to noninvasively interrogate plaque composition and disease activity, thereby differentiating stable from unstable patterns of disease and potentially improving risk stratification. This manuscript reviews multimodality imaging in this field, focusing on carotid and coronary atherosclerosis and how these novel techniques have the potential to complement current imaging assessments and improve clinical decision making.

Original languageEnglish
Pages (from-to)1055-1068
Number of pages14
JournalJACC: Cardiovascular Imaging
Issue number4
StatePublished - Apr 2020


  • atherosclerosis
  • plaque burden
  • positron emission tomography
  • vulnerable plaque


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