Non-T, non-B acute lymphoblastic leukemia (L3) with t(8;22) and two 14q+ chromosomes

R. S.K. Chaganti; Suresh C. Jhanwar; Zalmen Arlin; Benjamin Koziner; Appaji Ambati; Michael Andreeff; Bayard D. Clarkson

doi:10.1016/0165-4608(83)90110-3

Non-T, non-B acute lymphoblastic leukemia (L3) with t(8;22) and two 14q+ chromosomes

R. S.K. Chaganti
, Suresh C. Jhanwar
, Zalmen Arlin
, Benjamin Koziner
, Appaji Ambati
, Michael Andreeff
, Bayard D. Clarkson

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

A patient with L3 leukemia is reported whose leukemic cells were characterized cytogenetically by a duplication of the long arm segment 1q25→q42, trisomy for chromosome 7, t(8;22)(q24;q11), and two 14q+ chromosomes. Immunologic marker analysis revealed the leukemic cells to be of the non-T, non-B ("null") type. This observation, when considered in conjunction with a previous report of heterogeneity in cell lineages of L3 leukemias, raises the possibility of some lymphoid neoplasms arising in stem cells.

Original language	English
Pages (from-to)	95-103
Number of pages	9
Journal	Cancer Genetics and Cytogenetics
Volume	10
Issue number	1
DOIs	https://doi.org/10.1016/0165-4608(83)90110-3
State	Published - Sep 1983
Externally published	Yes

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title = "Non-T, non-B acute lymphoblastic leukemia (L3) with t(8;22) and two 14q+ chromosomes",

abstract = "A patient with L3 leukemia is reported whose leukemic cells were characterized cytogenetically by a duplication of the long arm segment 1q25→q42, trisomy for chromosome 7, t(8;22)(q24;q11), and two 14q+ chromosomes. Immunologic marker analysis revealed the leukemic cells to be of the non-T, non-B ({"}null{"}) type. This observation, when considered in conjunction with a previous report of heterogeneity in cell lineages of L3 leukemias, raises the possibility of some lymphoid neoplasms arising in stem cells.",

author = "Chaganti, \{R. S.K.\} and Jhanwar, \{Suresh C.\} and Zalmen Arlin and Benjamin Koziner and Appaji Ambati and Michael Andreeff and Clarkson, \{Bayard D.\}",

year = "1983",

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doi = "10.1016/0165-4608(83)90110-3",

language = "English",

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T1 - Non-T, non-B acute lymphoblastic leukemia (L3) with t(8;22) and two 14q+ chromosomes

AU - Chaganti, R. S.K.

AU - Jhanwar, Suresh C.

AU - Arlin, Zalmen

AU - Koziner, Benjamin

AU - Ambati, Appaji

AU - Andreeff, Michael

AU - Clarkson, Bayard D.

PY - 1983/9

Y1 - 1983/9

N2 - A patient with L3 leukemia is reported whose leukemic cells were characterized cytogenetically by a duplication of the long arm segment 1q25→q42, trisomy for chromosome 7, t(8;22)(q24;q11), and two 14q+ chromosomes. Immunologic marker analysis revealed the leukemic cells to be of the non-T, non-B ("null") type. This observation, when considered in conjunction with a previous report of heterogeneity in cell lineages of L3 leukemias, raises the possibility of some lymphoid neoplasms arising in stem cells.

AB - A patient with L3 leukemia is reported whose leukemic cells were characterized cytogenetically by a duplication of the long arm segment 1q25→q42, trisomy for chromosome 7, t(8;22)(q24;q11), and two 14q+ chromosomes. Immunologic marker analysis revealed the leukemic cells to be of the non-T, non-B ("null") type. This observation, when considered in conjunction with a previous report of heterogeneity in cell lineages of L3 leukemias, raises the possibility of some lymphoid neoplasms arising in stem cells.

UR - https://www.scopus.com/pages/publications/0020624471

U2 - 10.1016/0165-4608(83)90110-3

DO - 10.1016/0165-4608(83)90110-3

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C2 - 6576853

AN - SCOPUS:0020624471

SN - 0165-4608

VL - 10

SP - 95

EP - 103

JO - Cancer Genetics and Cytogenetics

JF - Cancer Genetics and Cytogenetics

IS - 1

ER -

Non-T, non-B acute lymphoblastic leukemia (L3) with t(8;22) and two 14q+ chromosomes

Abstract

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