Non-invasive low intensity ultrasound accelerates bone repair: Rabbit fibula model and human Colles' and tibial fractures

A. A. Pilla, M. Figueiredo, P. Nasser, S. Lattuga, T. Kristiansen, J. Heckman, J. J. Kaufman, R. S. Siffert

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Low-intensity pulsed ultrasound (US) was noninvasively applied to one limb of the bilateral osteotomized fibulae of 156 mature female New Zealand white rabbits. The effect of US input intensity and the effect of the electric and electromagnetic field associated with US generation were determined. Also presented is a summary of the preliminary clinical data for human Colles' and tibia diaphysis fractures. The US treatment of the osteotomized rabbit fibula caused an overall acceleration of healing by a factor of nearly 1.7. The power dosimetry study showed a typical dose response, suggesting that the bone penetration by the US signal must be taken into account for an adequate bioeffect to be achieved. Double-blind clinical studies showed that US could indeed be applied to enhance the rate of fracture repair.

Original languageEnglish
Title of host publicationBiomedical Engineering Perspectives
Subtitle of host publicationHealth Care Technologies for the 1990's and Beyond
PublisherPubl by IEEE
Pages1573-1574
Number of pages2
Editionpt 4
ISBN (Print)0879425598
StatePublished - 1990
EventProceedings of the 12th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Philadelphia, PA, USA
Duration: 1 Nov 19904 Nov 1990

Publication series

NameProceedings of the Annual Conference on Engineering in Medicine and Biology
Numberpt 4
ISSN (Print)0589-1019

Conference

ConferenceProceedings of the 12th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
CityPhiladelphia, PA, USA
Period1/11/904/11/90

Fingerprint

Dive into the research topics of 'Non-invasive low intensity ultrasound accelerates bone repair: Rabbit fibula model and human Colles' and tibial fractures'. Together they form a unique fingerprint.

Cite this