Non-Hodgkin's lymphoma of mucosa-associated lymphoid tissue

Seth M. Cohen, Magdalena Petryk, Mala Varma, Peter S. Kozuch, Elizabeth D. Ames, Michael L. Grossbard

Research output: Contribution to journalReview articlepeer-review

70 Scopus citations

Abstract

The concept of mucosa-associated lymphoid tissue (MALT) lymphomas was introduced by Isaacson and Wright [Cancer 1983;52:1410-1416] in 1983. After more than 20 years of clinical research MALT lymphomas are now recognized as a distinct subtype of non-Hodgkin's lymphoma (NHL) with unique pathogenic, histological, and clinical features. Although this subtype of NHL occurs frequently, optimal management remains elusive. This manuscript reviews features of the clinical presentation, diagnosis, pathology, molecular characteristics, and management of both gastric and non-gastric MALT lymphoma.

Original languageEnglish
Pages (from-to)1100-1117
Number of pages18
JournalOncologist
Volume11
Issue number10
DOIs
StatePublished - Nov 2006
Externally publishedYes

Keywords

  • Helicobacter pylori
  • Mucosa-associated lymphoid tissue
  • Non-Hodgkin's lymphoma

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