No association between the Ser9Gly polymorphism of the dopamine D3 receptor gene and schizophrenia in a Spanish sample

C. Vaquero Lorenzo; E. Baca-Garcia; M. Diaz Hernandez; C. Botillo Martin; M. M. Perez-Rodriguez; M. D. Saiz-Gonzalez; P. Fernández; F. J. Quintero Gutierrez; J. Saiz-Ruiz; J. Fernandez Piqueras; J. L. Gonzalez De Rivera; J. De Leon

doi:10.1002/ajmg.b.30331

No association between the Ser9Gly polymorphism of the dopamine D3 receptor gene and schizophrenia in a Spanish sample

C. Vaquero Lorenzo
, E. Baca-Garcia
, M. Diaz Hernandez
, C. Botillo Martin
, M. M. Perez-Rodriguez
, M. D. Saiz-Gonzalez
, P. Fernández
, F. J. Quintero Gutierrez
, J. Saiz-Ruiz
, J. Fernandez Piqueras
, J. L. Gonzalez De Rivera
, J. De Leon

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

This study aims to further evaluate the controversial association between the Ser9Gly polymorphism in codon 9 of the D3 dopamine receptor gene (DRD3) and schizophrenia in psychiatric inpatients acutely hospitalized in two general hospitals in Madrid, Spain. The Ser9Gly polymorphism of the DRD3 was examined in 178 schizophrenic patients, 286 patients with other psychiatric diagnoses, and 132 controls recruited. Genotype frequencies were in Hardy-Weinberg equilibrium. No association was found between schizophrenia and the Ser9Gly polymorphism of the D3 dopamine receptor gene.

Original language	English
Pages (from-to)	344-346
Number of pages	3
Journal	American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics
Volume	144
Issue number	3
DOIs	https://doi.org/10.1002/ajmg.b.30331
State	Published - 5 Apr 2007
Externally published	Yes

Keywords

Association study
DRD3 gene
Genetics
Schizophrenia

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10.1002/ajmg.b.30331

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Vaquero Lorenzo, C., Baca-Garcia, E., Diaz Hernandez, M., Botillo Martin, C., Perez-Rodriguez, M. M., Saiz-Gonzalez, M. D., Fernández, P., Quintero Gutierrez, F. J., Saiz-Ruiz, J., Fernandez Piqueras, J., Gonzalez De Rivera, J. L., & De Leon, J. (2007). No association between the Ser9Gly polymorphism of the dopamine D3 receptor gene and schizophrenia in a Spanish sample. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, 144(3), 344-346. https://doi.org/10.1002/ajmg.b.30331

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title = "No association between the Ser9Gly polymorphism of the dopamine D3 receptor gene and schizophrenia in a Spanish sample",

abstract = "This study aims to further evaluate the controversial association between the Ser9Gly polymorphism in codon 9 of the D3 dopamine receptor gene (DRD3) and schizophrenia in psychiatric inpatients acutely hospitalized in two general hospitals in Madrid, Spain. The Ser9Gly polymorphism of the DRD3 was examined in 178 schizophrenic patients, 286 patients with other psychiatric diagnoses, and 132 controls recruited. Genotype frequencies were in Hardy-Weinberg equilibrium. No association was found between schizophrenia and the Ser9Gly polymorphism of the D3 dopamine receptor gene.",

keywords = "Association study, DRD3 gene, Genetics, Schizophrenia",

author = "\{Vaquero Lorenzo\}, C. and E. Baca-Garcia and \{Diaz Hernandez\}, M. and \{Botillo Martin\}, C. and Perez-Rodriguez, \{M. M.\} and Saiz-Gonzalez, \{M. D.\} and P. Fern{\'a}ndez and \{Quintero Gutierrez\}, \{F. J.\} and J. Saiz-Ruiz and \{Fernandez Piqueras\}, J. and \{Gonzalez De Rivera\}, \{J. L.\} and \{De Leon\}, J.",

year = "2007",

month = apr,

day = "5",

doi = "10.1002/ajmg.b.30331",

language = "English",

volume = "144",

pages = "344--346",

journal = "American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics",

issn = "1552-4841",

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number = "3",

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Vaquero Lorenzo, C, Baca-Garcia, E, Diaz Hernandez, M, Botillo Martin, C, Perez-Rodriguez, MM, Saiz-Gonzalez, MD, Fernández, P, Quintero Gutierrez, FJ, Saiz-Ruiz, J, Fernandez Piqueras, J, Gonzalez De Rivera, JL & De Leon, J 2007, 'No association between the Ser9Gly polymorphism of the dopamine D3 receptor gene and schizophrenia in a Spanish sample', American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, vol. 144, no. 3, pp. 344-346. https://doi.org/10.1002/ajmg.b.30331

No association between the Ser9Gly polymorphism of the dopamine D3 receptor gene and schizophrenia in a Spanish sample. / Vaquero Lorenzo, C.; Baca-Garcia, E.; Diaz Hernandez, M. et al.
In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, Vol. 144, No. 3, 05.04.2007, p. 344-346.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - No association between the Ser9Gly polymorphism of the dopamine D3 receptor gene and schizophrenia in a Spanish sample

AU - Vaquero Lorenzo, C.

AU - Baca-Garcia, E.

AU - Diaz Hernandez, M.

AU - Botillo Martin, C.

AU - Perez-Rodriguez, M. M.

AU - Saiz-Gonzalez, M. D.

AU - Fernández, P.

AU - Quintero Gutierrez, F. J.

AU - Saiz-Ruiz, J.

AU - Fernandez Piqueras, J.

AU - Gonzalez De Rivera, J. L.

AU - De Leon, J.

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KW - Association study

KW - DRD3 gene

KW - Genetics

KW - Schizophrenia

UR - https://www.scopus.com/pages/publications/34247402055

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AN - SCOPUS:34247402055

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JO - American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics

JF - American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics

IS - 3

ER -

No association between the Ser9Gly polymorphism of the dopamine D3 receptor gene and schizophrenia in a Spanish sample

Abstract

Keywords

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