NMR assignment of the N-terminal region of human La free and in complex with RNA

Domenico Sanfelice, Geoff Kelly, Stephen Curry, Maria R. Conte

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

1H, 15N and 13C chemical shift assignments are presented for the N-terminal region of human La protein, in the apo and 5andacute;-UUUU RNA-bound state. Secondary structure analysis shows conformational changes in the interdomain linker upon complex formation.

Original languageEnglish
Pages (from-to)107-109
Number of pages3
JournalBiomolecular NMR Assignments
Volume2
Issue number2
DOIs
StatePublished - Dec 2008
Externally publishedYes

Keywords

  • La autoantigen
  • NMR resonance assignment
  • RNA interaction

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