Nitrogen vapor shipment of vitrified oocytes: Time for caution

Casey A. McDonald, Lora Valluzo, Lesley Chuang, Flora Poleshchuk, Alan B. Copperman, Jason Barritt

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


Oocyte cryopreservation for fertility preservation, in both medical and elective situations, has significantly increased as freezing technology has improved. Slow freezing techniques demonstrated ∼50-80% survival of mature oocytes, however vitrification with ∼97% survival has become the preferred method for oocyte cryopreservation around the world. Our work investigated the effect of transporting cryopreserved oocytes to and from a long-term storage facility. Our findings demonstrate that extra caution should be practiced for vitrified oocytes, especially when handling and transferring between shipping and long-term cryopreservation storage containers.

Original languageEnglish
Pages (from-to)2628-2630
Number of pages3
JournalFertility and Sterility
Issue number8
StatePublished - 30 Jun 2011


  • Oocyte cryopreservation
  • egg freezing
  • fertility preservation
  • tissue transport
  • vitrification


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