Nitric oxide in the painful bladder/interstitial cystitis

Lotta Renström Koskela, N. P. Wiklund

Research output: Contribution to journalArticlepeer-review

Abstract

Interstitial cystitis (IC) is an inflammatory disease of the urinary bladder of unknown etiology. Nitric oxide (NO) is a useful gas in detecting inflammation in hollow organs such as the urinary bladder. In patients with IC the levels of endogenously formed NO in the bladder are significantly increased compared to patients without inflammation of the bladder. It still remains unknown whether high levels of NO is a part of the pathophysiology of this disease and whether it has a damaging or protective role. Measuring NO in the urinary bladder is a useful tool in detecting inflammation, thus making it possible to discriminate between interstitial cystitis and painful bladder symptoms of other etiology. It can also be used in the objective evaluation of different treatments.

Original languageEnglish
Pages (from-to)18-19
Number of pages2
JournalJournal fur Urologie und Urogynakologie
Volume14
Issue number1
StatePublished - 2007

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