New recognition of Enterovirus infections in bottlenose dolphins (Tursiops truncatus)

Hendrik H. Nollens; Rebecca Rivera; Gustavo Palacios; James F.X. Wellehan; Jeremiah T. Saliki; Shannon L. Caseltine; Cynthia R. Smith; Eric D. Jensen; Jeffrey Hui; W. Ian Lipkin; Pamela K. Yochem; Randall S. Wells; Judy St. Leger; Stephanie Venn-Watson

doi:10.1016/j.vetmic.2009.05.010

New recognition of Enterovirus infections in bottlenose dolphins (Tursiops truncatus)

Hendrik H. Nollens, Rebecca Rivera, Gustavo Palacios, James F.X. Wellehan, Jeremiah T. Saliki, Shannon L. Caseltine, Cynthia R. Smith, Eric D. Jensen, Jeffrey Hui, W. Ian Lipkin, Pamela K. Yochem, Randall S. Wells, Judy St. Leger, Stephanie Venn-Watson

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

An enterovirus was cultured from an erosive tongue lesion of a bottlenose dolphin (Tursiops truncatus). The morphology of virions on negative staining electron microscopy was consistent with those of enteroviruses. Analysis of 2613 bp of the polyprotein gene identified the isolate as a novel enterovirus strain, tentatively named bottlenose dolphin enterovirus (BDEV), that nests within the species Bovine enterovirus. Serologic evidence of exposure to enteroviruses was common in both free-ranging and managed collection dolphins. Managed collection dolphins were more likely to have high antibody levels, although the highest levels were reported in free-ranging populations. Associations between enterovirus antibody levels, and age, sex, complete blood counts, and clinical serum biochemistries were explored. Dolphins with higher antibody levels were more likely to be hyperproteinemic and hyperglobulinemic.

Original language	English
Pages (from-to)	170-175
Number of pages	6
Journal	Veterinary Microbiology
Volume	139
Issue number	1-2
DOIs	https://doi.org/10.1016/j.vetmic.2009.05.010
State	Published - 20 Oct 2009
Externally published	Yes

Keywords

Bovine enterovirus
Dolphin
Pathogen
Tursiops
Virus

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10.1016/j.vetmic.2009.05.010

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Nollens, H. H., Rivera, R., Palacios, G., Wellehan, J. F. X., Saliki, J. T., Caseltine, S. L., Smith, C. R., Jensen, E. D., Hui, J., Lipkin, W. I., Yochem, P. K., Wells, R. S., St. Leger, J., & Venn-Watson, S. (2009). New recognition of Enterovirus infections in bottlenose dolphins (Tursiops truncatus). Veterinary Microbiology, 139(1-2), 170-175. https://doi.org/10.1016/j.vetmic.2009.05.010

@article{efad789772d44464a8b887015648acb9,

title = "New recognition of Enterovirus infections in bottlenose dolphins (Tursiops truncatus)",

abstract = "An enterovirus was cultured from an erosive tongue lesion of a bottlenose dolphin (Tursiops truncatus). The morphology of virions on negative staining electron microscopy was consistent with those of enteroviruses. Analysis of 2613 bp of the polyprotein gene identified the isolate as a novel enterovirus strain, tentatively named bottlenose dolphin enterovirus (BDEV), that nests within the species Bovine enterovirus. Serologic evidence of exposure to enteroviruses was common in both free-ranging and managed collection dolphins. Managed collection dolphins were more likely to have high antibody levels, although the highest levels were reported in free-ranging populations. Associations between enterovirus antibody levels, and age, sex, complete blood counts, and clinical serum biochemistries were explored. Dolphins with higher antibody levels were more likely to be hyperproteinemic and hyperglobulinemic.",

keywords = "Bovine enterovirus, Dolphin, Pathogen, Tursiops, Virus",

author = "Nollens, {Hendrik H.} and Rebecca Rivera and Gustavo Palacios and Wellehan, {James F.X.} and Saliki, {Jeremiah T.} and Caseltine, {Shannon L.} and Smith, {Cynthia R.} and Jensen, {Eric D.} and Jeffrey Hui and Lipkin, {W. Ian} and Yochem, {Pamela K.} and Wells, {Randall S.} and {St. Leger}, Judy and Stephanie Venn-Watson",

note = "Funding Information: This work was funded by research grant no. N00014-06-1-0250 to HN from the Office of Naval Research. Authors GP, JH and WIL were supported by NIH awards AI1057158, HL083850, and AI070411. Field sampling was conducted under NMFS Research Permit No. 522-1569 to RW. ",

year = "2009",

month = oct,

day = "20",

doi = "10.1016/j.vetmic.2009.05.010",

language = "English",

volume = "139",

pages = "170--175",

journal = "Veterinary Microbiology",

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Nollens, HH, Rivera, R, Palacios, G, Wellehan, JFX, Saliki, JT, Caseltine, SL, Smith, CR, Jensen, ED, Hui, J, Lipkin, WI, Yochem, PK, Wells, RS, St. Leger, J & Venn-Watson, S 2009, 'New recognition of Enterovirus infections in bottlenose dolphins (Tursiops truncatus)', Veterinary Microbiology, vol. 139, no. 1-2, pp. 170-175. https://doi.org/10.1016/j.vetmic.2009.05.010

TY - JOUR

T1 - New recognition of Enterovirus infections in bottlenose dolphins (Tursiops truncatus)

AU - Nollens, Hendrik H.

AU - Rivera, Rebecca

AU - Palacios, Gustavo

AU - Wellehan, James F.X.

AU - Saliki, Jeremiah T.

AU - Caseltine, Shannon L.

AU - Smith, Cynthia R.

AU - Jensen, Eric D.

AU - Hui, Jeffrey

AU - Lipkin, W. Ian

AU - Yochem, Pamela K.

AU - Wells, Randall S.

AU - St. Leger, Judy

AU - Venn-Watson, Stephanie

N1 - Funding Information: This work was funded by research grant no. N00014-06-1-0250 to HN from the Office of Naval Research. Authors GP, JH and WIL were supported by NIH awards AI1057158, HL083850, and AI070411. Field sampling was conducted under NMFS Research Permit No. 522-1569 to RW.

PY - 2009/10/20

Y1 - 2009/10/20

N2 - An enterovirus was cultured from an erosive tongue lesion of a bottlenose dolphin (Tursiops truncatus). The morphology of virions on negative staining electron microscopy was consistent with those of enteroviruses. Analysis of 2613 bp of the polyprotein gene identified the isolate as a novel enterovirus strain, tentatively named bottlenose dolphin enterovirus (BDEV), that nests within the species Bovine enterovirus. Serologic evidence of exposure to enteroviruses was common in both free-ranging and managed collection dolphins. Managed collection dolphins were more likely to have high antibody levels, although the highest levels were reported in free-ranging populations. Associations between enterovirus antibody levels, and age, sex, complete blood counts, and clinical serum biochemistries were explored. Dolphins with higher antibody levels were more likely to be hyperproteinemic and hyperglobulinemic.

AB - An enterovirus was cultured from an erosive tongue lesion of a bottlenose dolphin (Tursiops truncatus). The morphology of virions on negative staining electron microscopy was consistent with those of enteroviruses. Analysis of 2613 bp of the polyprotein gene identified the isolate as a novel enterovirus strain, tentatively named bottlenose dolphin enterovirus (BDEV), that nests within the species Bovine enterovirus. Serologic evidence of exposure to enteroviruses was common in both free-ranging and managed collection dolphins. Managed collection dolphins were more likely to have high antibody levels, although the highest levels were reported in free-ranging populations. Associations between enterovirus antibody levels, and age, sex, complete blood counts, and clinical serum biochemistries were explored. Dolphins with higher antibody levels were more likely to be hyperproteinemic and hyperglobulinemic.

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KW - Dolphin

KW - Pathogen

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VL - 139

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EP - 175

JO - Veterinary Microbiology

JF - Veterinary Microbiology

IS - 1-2

ER -

New recognition of Enterovirus infections in bottlenose dolphins (Tursiops truncatus)

Abstract

Keywords

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