New driver for lipid synthesis

Sander M. Houten; Carmen A. Argmann

doi:10.1016/j.cell.2011.10.019

New driver for lipid synthesis

Research output: Contribution to journal › Short survey › peer-review

2 Scopus citations

Abstract

Cholesterol regulates activation of sterol regulatory element-binding protein (SREBP) through a classic feedback loop. Walker et al. (2011) extend the regulatory inputs governing SREBP activity to include an independent loop modulated by phosphatidylcholine (PC) and cellular methylation capacity. These findings suggest a link between lipid synthesis and cellular pathways involved in methylation.

Original language	English
Pages (from-to)	719-721
Number of pages	3
Journal	Cell
Volume	147
Issue number	4
DOIs	https://doi.org/10.1016/j.cell.2011.10.019
State	Published - 11 Nov 2011
Externally published	Yes

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10.1016/j.cell.2011.10.019

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title = "New driver for lipid synthesis",

abstract = "Cholesterol regulates activation of sterol regulatory element-binding protein (SREBP) through a classic feedback loop. Walker et al. (2011) extend the regulatory inputs governing SREBP activity to include an independent loop modulated by phosphatidylcholine (PC) and cellular methylation capacity. These findings suggest a link between lipid synthesis and cellular pathways involved in methylation.",

author = "Houten, \{Sander M.\} and Argmann, \{Carmen A.\}",

year = "2011",

month = nov,

day = "11",

doi = "10.1016/j.cell.2011.10.019",

language = "English",

volume = "147",

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journal = "Cell",

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publisher = "Elsevier B.V.",

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TY - JOUR

T1 - New driver for lipid synthesis

AU - Houten, Sander M.

AU - Argmann, Carmen A.

PY - 2011/11/11

Y1 - 2011/11/11

N2 - Cholesterol regulates activation of sterol regulatory element-binding protein (SREBP) through a classic feedback loop. Walker et al. (2011) extend the regulatory inputs governing SREBP activity to include an independent loop modulated by phosphatidylcholine (PC) and cellular methylation capacity. These findings suggest a link between lipid synthesis and cellular pathways involved in methylation.

AB - Cholesterol regulates activation of sterol regulatory element-binding protein (SREBP) through a classic feedback loop. Walker et al. (2011) extend the regulatory inputs governing SREBP activity to include an independent loop modulated by phosphatidylcholine (PC) and cellular methylation capacity. These findings suggest a link between lipid synthesis and cellular pathways involved in methylation.

UR - https://www.scopus.com/pages/publications/81055129625

U2 - 10.1016/j.cell.2011.10.019

DO - 10.1016/j.cell.2011.10.019

M3 - Short survey

AN - SCOPUS:81055129625

SN - 0092-8674

VL - 147

SP - 719

EP - 721

JO - Cell

JF - Cell

IS - 4

ER -

New driver for lipid synthesis

Abstract

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