TY - JOUR
T1 - New approaches in brain morphometry
AU - Toga, Arthur W.
AU - Thompson, Paul M.
N1 - Funding Information:
This work was generously supported by research grants from the National Library of Medicine (LM/MH05639), National Center for Research Resources (RR13642), and by a Human Brain Project grant known as the International Consortium for Brain Mapping, which is funded jointly by NIMH and NIDA (P20 MH/DA52176).
PY - 2002
Y1 - 2002
N2 - The complexity and variability of the human brain across subjects is so great that reliance on maps and atlases is essential to effectively manipulate, analyze, and interpret brain data. Central to these tasks is the construction of averages, templates, and models to describe how the brain and its component parts are organized. Design of appropriate reference systems for human brain data presents considerable challenges because these systems must capture how brain structure and function vary in large populations, across age and gender, in different disease states, across imaging modalities, and even across species. The authors introduce the topic of brain maps as applied to a variety of questions and problems in health and disease and include a brief survey of the types of maps relevant to mental disorders, including maps that capture dynamic patterns of brain change in dementia.
AB - The complexity and variability of the human brain across subjects is so great that reliance on maps and atlases is essential to effectively manipulate, analyze, and interpret brain data. Central to these tasks is the construction of averages, templates, and models to describe how the brain and its component parts are organized. Design of appropriate reference systems for human brain data presents considerable challenges because these systems must capture how brain structure and function vary in large populations, across age and gender, in different disease states, across imaging modalities, and even across species. The authors introduce the topic of brain maps as applied to a variety of questions and problems in health and disease and include a brief survey of the types of maps relevant to mental disorders, including maps that capture dynamic patterns of brain change in dementia.
UR - http://www.scopus.com/inward/record.url?scp=0036142081&partnerID=8YFLogxK
U2 - 10.1097/00019442-200201000-00003
DO - 10.1097/00019442-200201000-00003
M3 - Article
AN - SCOPUS:0036142081
SN - 1064-7481
VL - 10
SP - 13
EP - 23
JO - American Journal of Geriatric Psychiatry
JF - American Journal of Geriatric Psychiatry
IS - 1
ER -