Neurotransmitter dysfunction in patients with borderline personality disorder

Irene G. Gurvits; Harold W. Koenigsberg; Larry J. Siever

doi:10.1016/S0193-953X(05)70141-6

Neurotransmitter dysfunction in patients with borderline personality disorder

Irene G. Gurvits
, Harold W. Koenigsberg
, Larry J. Siever

Research output: Contribution to journal › Article › peer-review

101 Scopus citations

Abstract

Neurotransmitter system dysfunction may contribute to the borderline personality disorder traits of impulsive aggression and affective instability. This article reviews evidence from neurochemical assays, receptor-density studies, neuroendocrine challenge paradigms, functional neuroimaging studies, and candidate-gene research, which converge to identify particular neurotransmitter systems that seem to be dysregulated in patients with borderline personality disorder.

Original language	English
Pages (from-to)	27-40
Number of pages	14
Journal	Psychiatric Clinics of North America
Volume	23
Issue number	1
DOIs	https://doi.org/10.1016/S0193-953X(05)70141-6
State	Published - 2000

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title = "Neurotransmitter dysfunction in patients with borderline personality disorder",

abstract = "Neurotransmitter system dysfunction may contribute to the borderline personality disorder traits of impulsive aggression and affective instability. This article reviews evidence from neurochemical assays, receptor-density studies, neuroendocrine challenge paradigms, functional neuroimaging studies, and candidate-gene research, which converge to identify particular neurotransmitter systems that seem to be dysregulated in patients with borderline personality disorder.",

author = "Gurvits, \{Irene G.\} and Koenigsberg, \{Harold W.\} and Siever, \{Larry J.\}",

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AU - Siever, Larry J.

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AB - Neurotransmitter system dysfunction may contribute to the borderline personality disorder traits of impulsive aggression and affective instability. This article reviews evidence from neurochemical assays, receptor-density studies, neuroendocrine challenge paradigms, functional neuroimaging studies, and candidate-gene research, which converge to identify particular neurotransmitter systems that seem to be dysregulated in patients with borderline personality disorder.

UR - https://www.scopus.com/pages/publications/0034056827

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DO - 10.1016/S0193-953X(05)70141-6

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JO - Psychiatric Clinics of North America

JF - Psychiatric Clinics of North America

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ER -

Neurotransmitter dysfunction in patients with borderline personality disorder

Abstract

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