TY - JOUR
T1 - Neurotransmitter dysfunction in patients with borderline personality disorder
AU - Gurvits, Irene G.
AU - Koenigsberg, Harold W.
AU - Siever, Larry J.
PY - 2000
Y1 - 2000
N2 - Neurotransmitter system dysfunction may contribute to the borderline personality disorder traits of impulsive aggression and affective instability. This article reviews evidence from neurochemical assays, receptor-density studies, neuroendocrine challenge paradigms, functional neuroimaging studies, and candidate-gene research, which converge to identify particular neurotransmitter systems that seem to be dysregulated in patients with borderline personality disorder.
AB - Neurotransmitter system dysfunction may contribute to the borderline personality disorder traits of impulsive aggression and affective instability. This article reviews evidence from neurochemical assays, receptor-density studies, neuroendocrine challenge paradigms, functional neuroimaging studies, and candidate-gene research, which converge to identify particular neurotransmitter systems that seem to be dysregulated in patients with borderline personality disorder.
UR - http://www.scopus.com/inward/record.url?scp=0034056827&partnerID=8YFLogxK
U2 - 10.1016/S0193-953X(05)70141-6
DO - 10.1016/S0193-953X(05)70141-6
M3 - Article
C2 - 10729929
AN - SCOPUS:0034056827
SN - 0193-953X
VL - 23
SP - 27
EP - 40
JO - Psychiatric Clinics of North America
JF - Psychiatric Clinics of North America
IS - 1
ER -