Neurological implications of COVID-19: A review of the science and clinical guidance

Lynn Tan; Zhiliang Caleb Lin; Jason Ray; Robb Wesselingh; Thomas J. Oxley; James McFadyen; Mahima Kapoor; Elspeth Hutton

doi:10.1136/bmjno-2020-000101

Neurological implications of COVID-19: A review of the science and clinical guidance

Lynn Tan, Zhiliang Caleb Lin, Jason Ray, Robb Wesselingh, Thomas J. Oxley, James McFadyen, Mahima Kapoor, Elspeth Hutton

Research output: Contribution to journal › Review article › peer-review

4 Scopus citations

Abstract

COVID-19 is a significant global health burden. The pulmonary morbidity and mortality of COVID-19 is well described, however, there is mounting evidence of neurological manifestations of SARS-CoV-2, which may be of prognostic significance. This paper summarises the available evidence in order to provide clinicians with a concise summary of the peripheral and central neurological manifestations of COVID-19, discusses specific issues regarding the management of chronic neurological disease in the context of the pandemic, and provides a summary of the thrombotic implications of the disease for the neurologist.

Original language	English
Article number	e000101
Journal	BMJ Neurology Open
Volume	2
Issue number	2
DOIs	https://doi.org/10.1136/bmjno-2020-000101
State	Published - 14 Dec 2020

Keywords

clinical neurology
stroke

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title = "Neurological implications of COVID-19: A review of the science and clinical guidance",

abstract = "COVID-19 is a significant global health burden. The pulmonary morbidity and mortality of COVID-19 is well described, however, there is mounting evidence of neurological manifestations of SARS-CoV-2, which may be of prognostic significance. This paper summarises the available evidence in order to provide clinicians with a concise summary of the peripheral and central neurological manifestations of COVID-19, discusses specific issues regarding the management of chronic neurological disease in the context of the pandemic, and provides a summary of the thrombotic implications of the disease for the neurologist.",

keywords = "clinical neurology, stroke",

author = "Lynn Tan and Lin, {Zhiliang Caleb} and Jason Ray and Robb Wesselingh and Oxley, {Thomas J.} and James McFadyen and Mahima Kapoor and Elspeth Hutton",

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T2 - A review of the science and clinical guidance

AU - Tan, Lynn

AU - Lin, Zhiliang Caleb

AU - Ray, Jason

AU - Wesselingh, Robb

AU - Oxley, Thomas J.

AU - McFadyen, James

AU - Kapoor, Mahima

AU - Hutton, Elspeth

PY - 2020/12/14

Y1 - 2020/12/14

N2 - COVID-19 is a significant global health burden. The pulmonary morbidity and mortality of COVID-19 is well described, however, there is mounting evidence of neurological manifestations of SARS-CoV-2, which may be of prognostic significance. This paper summarises the available evidence in order to provide clinicians with a concise summary of the peripheral and central neurological manifestations of COVID-19, discusses specific issues regarding the management of chronic neurological disease in the context of the pandemic, and provides a summary of the thrombotic implications of the disease for the neurologist.

AB - COVID-19 is a significant global health burden. The pulmonary morbidity and mortality of COVID-19 is well described, however, there is mounting evidence of neurological manifestations of SARS-CoV-2, which may be of prognostic significance. This paper summarises the available evidence in order to provide clinicians with a concise summary of the peripheral and central neurological manifestations of COVID-19, discusses specific issues regarding the management of chronic neurological disease in the context of the pandemic, and provides a summary of the thrombotic implications of the disease for the neurologist.

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KW - stroke

UR - http://www.scopus.com/inward/record.url?scp=85110821607&partnerID=8YFLogxK

U2 - 10.1136/bmjno-2020-000101

DO - 10.1136/bmjno-2020-000101

M3 - Review article

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VL - 2

JO - BMJ Neurology Open

JF - BMJ Neurology Open

IS - 2

M1 - e000101

ER -

Neurological implications of COVID-19: A review of the science and clinical guidance

Abstract

Keywords

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