TY - JOUR
T1 - Neurologic manifestations of HIV infection
AU - Simpson, D. M.
AU - Berger, J. R.
PY - 1996
Y1 - 1996
N2 - A wide spectrum of central and peripheral nervous system abnormalities may be associated with HIV infection. These disorders may be caused by HIV infection, result as secondary complications related to immunosuppression, or be a neurotoxic effect of therapeutic agents. The range of neurologic disorders includes dementia, focal cerebral mass lesions, myelopathy, peripheral neuropathies, and myopathy. Early diagnosis and therapy is critical, and may result in substantial improvement in patients' quality and quantity of life. This article reviews the approach to differential diagnosis of these neurologic disorders and presents theories of pathogenesis and current approaches to treatment.
AB - A wide spectrum of central and peripheral nervous system abnormalities may be associated with HIV infection. These disorders may be caused by HIV infection, result as secondary complications related to immunosuppression, or be a neurotoxic effect of therapeutic agents. The range of neurologic disorders includes dementia, focal cerebral mass lesions, myelopathy, peripheral neuropathies, and myopathy. Early diagnosis and therapy is critical, and may result in substantial improvement in patients' quality and quantity of life. This article reviews the approach to differential diagnosis of these neurologic disorders and presents theories of pathogenesis and current approaches to treatment.
UR - http://www.scopus.com/inward/record.url?scp=0029847426&partnerID=8YFLogxK
U2 - 10.1016/S0025-7125(05)70494-6
DO - 10.1016/S0025-7125(05)70494-6
M3 - Article
C2 - 8941227
AN - SCOPUS:0029847426
VL - 80
SP - 1363
EP - 1394
JO - Medical Clinics of North America
JF - Medical Clinics of North America
SN - 0025-7125
IS - 6
ER -