Neuraminidase and Free Sialic Acid Levels in Acute Poststreptococcal Glomerulonephritis

Owen Glenn Peller, Howard Fillit, Bernardo Rodríguez-Iturbe

Research output: Contribution to journalLetterpeer-review

Abstract

To the Editor:In the June 18 article by Rodríguez-Iturbe et al.,1 the authors acknowledged that they could not disregard the possibility that lipid peroxides contributed to the thiobarbituric acid (TBA) reactivity that was presumed to represent a measure of neuraminic acid levels in the serum of patients with acute poststreptococcal glomerulonephritis, but that they believed this to be unlikely. There is a good a priori reason to believe that lipid peroxidation products such as malondialdehyde (which is known to react with TBA) were present in abnormal concentrations in the blood of these patients. The deposition of immune complexes in.

Original languageEnglish
Pages (from-to)1016-1017
Number of pages2
JournalNew England Journal of Medicine
Volume305
Issue number17
DOIs
StatePublished - 22 Oct 1981
Externally publishedYes

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