TY - JOUR
T1 - Neural architecture of the vertebrate brain
T2 - implications for the interaction between emotion and cognition
AU - Pessoa, Luiz
AU - Medina, Loreta
AU - Hof, Patrick R.
AU - Desfilis, Ester
N1 - Publisher Copyright:
© 2019 Elsevier Ltd
PY - 2019/12
Y1 - 2019/12
N2 - Cognition is considered a hallmark of the primate brain that requires a high degree of signal integration, such as achieved in the prefrontal cortex. Moreover, it is often assumed that cognitive capabilities imply “superior” computational mechanisms compared to those involved in emotion or motivation. In contrast to these ideas, we review data on the neural architecture across vertebrates that support the concept that association and integration are basic features of the vertebrate brain, which are needed to successfully adapt to a changing world. This property is not restricted to a few isolated brain centers, but rather resides in neuronal networks working collectively in a context-dependent manner. In different vertebrates, we identify shared large-scale connectional systems involving the midbrain, hypothalamus, thalamus, basal ganglia, and amygdala. The high degree of crosstalk and association between these systems at different levels supports the notion that cognition, emotion, and motivation cannot be separated – all of them involve a high degree of signal integration.
AB - Cognition is considered a hallmark of the primate brain that requires a high degree of signal integration, such as achieved in the prefrontal cortex. Moreover, it is often assumed that cognitive capabilities imply “superior” computational mechanisms compared to those involved in emotion or motivation. In contrast to these ideas, we review data on the neural architecture across vertebrates that support the concept that association and integration are basic features of the vertebrate brain, which are needed to successfully adapt to a changing world. This property is not restricted to a few isolated brain centers, but rather resides in neuronal networks working collectively in a context-dependent manner. In different vertebrates, we identify shared large-scale connectional systems involving the midbrain, hypothalamus, thalamus, basal ganglia, and amygdala. The high degree of crosstalk and association between these systems at different levels supports the notion that cognition, emotion, and motivation cannot be separated – all of them involve a high degree of signal integration.
KW - Amygdala
KW - Basal ganglia
KW - Cognition
KW - Emotion
KW - Integration
KW - Vertebrate brain
UR - http://www.scopus.com/inward/record.url?scp=85072584512&partnerID=8YFLogxK
U2 - 10.1016/j.neubiorev.2019.09.021
DO - 10.1016/j.neubiorev.2019.09.021
M3 - Review article
C2 - 31541638
AN - SCOPUS:85072584512
SN - 0149-7634
VL - 107
SP - 296
EP - 312
JO - Neuroscience and Biobehavioral Reviews
JF - Neuroscience and Biobehavioral Reviews
ER -