Neonatal Marfan syndrome: In utero presentation with aortic and pulmonary artery dilatation and successful repair of an acute flail mitral valve leaflet in infancy

Prema Ramaswamy, Irena D. Lytrivi, Khanh Nguyen, Bruce D. Gelb

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

Neonatal Marfan syndrome (nMFS) is the rare and severe form of this connective tissue disorder with poor outcome due to progressive valvular insufficiency. We describe a case of nMFS suspected in utero, by fetal echocardiography, due to marked dilatation of both great arteries, which is the first description of fetal pulmonary artery dilatation in this disorder. The patient developed a flail mitral valve leaflet during the first year of life that was successfully repaired with an excellent medium-term result. This is the first report of this type of surgery in infancy.

Original languageEnglish
Pages (from-to)763-765
Number of pages3
JournalPediatric Cardiology
Volume27
Issue number6
DOIs
StatePublished - Dec 2006

Keywords

  • Fetus
  • Mitral valvuloplasty
  • Neonatal Marfan

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