Negative Pressure Wound Therapy in Spinal Surgery

Alexandra Jeanne White, Ronit Gilad, Soriaya Motivala, Brian Fiani, Jonathan Rasouli

Research output: Contribution to journalReview articlepeer-review


Negative pressure wound therapy (NPWT) has demonstrated promise in the management of surgical site infections as well as assisting in surgical wound healing. In this manuscript, we describe the mechanisms and applications of NPWT for surgical wounds and existing evidence for NPWT in cardiac, plastic, and general surgery, followed by a discussion of the emerging evidence base for NPWT in spinal surgery. We also discuss the different applications of NPWT for open wounds and closed incisions, and the promise of newer closed-incision NPWT (ciNPWT) devices. There is nominal but promising prospective evidence on NPWT’s efficacy in select at-risk populations for post-operative wound complications after spinal surgery. As there is currently a paucity of robust clinical evidence on its efficacy, rigorous randomized prospective clinical trials are needed.

Original languageEnglish
Article number614
Issue number11
StatePublished - Nov 2022
Externally publishedYes


  • infection prevention
  • spine surgery
  • surgical site infection
  • wound dressing
  • wound healing
  • wound management


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