Nearly a third of abnormalities found after first-trimester screening are different than expected:10-year experience from a single center

Medicine & Life Sciences

• Abnormal Karyotype 24%
• Aneuploidy 18%
• Chorionic Gonadotropin 9%
• Chromosome Aberrations 16%
• Chromosomes 6%
• Chromosomes, Human, Pair 13 11%
• Chromosomes, Human, Pair 18 12%
• Chromosomes, Human, Pair 21 11%
• Datasets 6%
• Down Syndrome 72%
• First Pregnancy Trimester 72%
• Karyotype 8%
• Maternal Age 9%
• Mothers 5%
• Nuchal Translucency Measurement 12%
• Pregnancy 10%
• Pregnancy-Associated Plasma Protein-A 12%
• Risk Assessment 7%
• Serum 3%
• Trisomy 13 Syndrome 100%
• Trisomy 18 Syndrome 95%