Naïve CD8⁺ t-cells engage a versatile metabolic program upon activation in humans and differ energetically from memory CD8⁺ T-cells

Keyphrases

• CD8+ T Cells 100%
• Nave 100%
• Metabolic Programming 100%
• Novel Immunotherapy 16%
• Gene Expression Profiling 16%
• Mammalian Target of Rapamycin (mTOR) 16%
• Autophagy 16%
• Lipid Acids 16%
• T Cell Receptor 16%
• Adaptive Immune Response 16%
• Metabolic 16%
• CD8+ T 16%
• Cellular Compartments 16%
• Fatty Acids 16%
• Ligation 16%
• Neutral Lipids 16%
• Metabolic Difference 16%
• Human Memory 16%
• Glycolytic Pathway 16%
• Biochemical Processes 16%
• Gene Expression Measurements 16%
• Differentiation Status 16%
• Energetic Requirements 16%
• Metabolic Determinants 16%
• Background Characterization 16%
• Nutrient Flux 16%
• Energetic Pathways 16%

Immunology and Microbiology

• CD8 100%
• Cytotoxic T-Cell 100%
• Immunotherapy 33%
• T Cell Receptor 33%
• Energy Transfer 33%
• Adaptive Immune System 16%
• Mediator 16%
• Precursor 16%
• Autophagy 16%
• Sirolimus 16%
• Gene Expression Assay 16%

Biochemistry, Genetics and Molecular Biology

• T Cell 100%
• CD8 100%
• T Cell Receptor 28%
• Energy Transfer 28%
• Precursor 14%
• Autophagy 14%
• Gene Expression Profiling 14%
• Mediator 14%
• Adaptive Immunity 14%
• Triglyceride 14%
• Mechanistic Target of Rapamycin 14%
• Biochemical Process 14%