Myopathies in HIV Infection

Mirela E. Toma, Alejandra Gonzalez-Duarte, David M. Simpson

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Original languageEnglish
Title of host publicationInternational Neurology
Subtitle of host publicationA Clinical Approach
Number of pages2
ISBN (Print)9781405157384
StatePublished - 18 May 2010


  • Electromyography (EMG), sensitive diagnostic test, up to 94% diagnostic yield
  • HIV-associated neuromuscular weakness (HANWS)
  • Immunohistological features, endomyseal infiltrates with CD8-positive cells, macrophages, and CD4-positive cells
  • Main clinical manifestation of HIV myopathy and NRTI myopathy
  • Muscle biopsy confirming diagnosis
  • Myopathies in HIV infection
  • Pathogenesis of HIV myopathy - immunological
  • Skeletal muscle involvement - at any stage of HIV infection, secondary to multiple causes

Cite this