Myocardial t1-mapping and extracellular volume quantification in patients and putative carriers of muscular dystrophy: Early experience

Kazuhiro Koyanagawa; Yuta Kobayashi; Tadao Aikawa; Atsuhito Takeda; Hideaki Shiraishi; Satonori Tsuneta; Noriko Oyama-Manabe; Hiroyuki Iwano; Toshiyuki Nagai; Toshihisa Anzai

doi:10.2463/mrms.bc.2020-0069

Myocardial t₁-mapping and extracellular volume quantification in patients and putative carriers of muscular dystrophy: Early experience

Kazuhiro Koyanagawa
, Yuta Kobayashi
, Tadao Aikawa
, Atsuhito Takeda
, Hideaki Shiraishi
, Satonori Tsuneta
, Noriko Oyama-Manabe
, Hiroyuki Iwano
, Toshiyuki Nagai
, Toshihisa Anzai

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

To assess myocardial fibrosis associated with muscular dystrophy, T₁-mapping and extracellular volume fraction (ECV) quantification was prospectively performed using cardiovascular MR (CMR) imaging in 6 male patients with muscular dystrophy and 5 female putative carriers of Duchenne or Becker muscular dys-trophy. Five patients and all putative carriers had an elevated ECV (>29.5% for men and >35.2% for women), suggesting that ECV has a potential to detect diffuse fibrotic changes in patients and putative carriers of muscular dystrophy.

Original language	English
Pages (from-to)	320-324
Number of pages	5
Journal	Magnetic Resonance in Medical Sciences
Volume	20
Issue number	3
DOIs	https://doi.org/10.2463/mrms.bc.2020-0069
State	Published - 2021
Externally published	Yes

Keywords

Cardiovascular magnetic resonance imaging
Extracellular volume fraction
Muscular dystrophy
Putative carrier
T-mapping

Access to Document

10.2463/mrms.bc.2020-0069

Cite this

Koyanagawa, K., Kobayashi, Y., Aikawa, T., Takeda, A., Shiraishi, H., Tsuneta, S., Oyama-Manabe, N., Iwano, H., Nagai, T., & Anzai, T. (2021). Myocardial t₁-mapping and extracellular volume quantification in patients and putative carriers of muscular dystrophy: Early experience. Magnetic Resonance in Medical Sciences, 20(3), 320-324. https://doi.org/10.2463/mrms.bc.2020-0069

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title = "Myocardial t1-mapping and extracellular volume quantification in patients and putative carriers of muscular dystrophy: Early experience",

abstract = "To assess myocardial fibrosis associated with muscular dystrophy, T1-mapping and extracellular volume fraction (ECV) quantification was prospectively performed using cardiovascular MR (CMR) imaging in 6 male patients with muscular dystrophy and 5 female putative carriers of Duchenne or Becker muscular dys-trophy. Five patients and all putative carriers had an elevated ECV (>29.5\% for men and >35.2\% for women), suggesting that ECV has a potential to detect diffuse fibrotic changes in patients and putative carriers of muscular dystrophy.",

keywords = "Cardiovascular magnetic resonance imaging, Extracellular volume fraction, Muscular dystrophy, Putative carrier, T-mapping",

author = "Kazuhiro Koyanagawa and Yuta Kobayashi and Tadao Aikawa and Atsuhito Takeda and Hideaki Shiraishi and Satonori Tsuneta and Noriko Oyama-Manabe and Hiroyuki Iwano and Toshiyuki Nagai and Toshihisa Anzai",

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doi = "10.2463/mrms.bc.2020-0069",

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Koyanagawa, K, Kobayashi, Y, Aikawa, T, Takeda, A, Shiraishi, H, Tsuneta, S, Oyama-Manabe, N, Iwano, H, Nagai, T & Anzai, T 2021, 'Myocardial t₁-mapping and extracellular volume quantification in patients and putative carriers of muscular dystrophy: Early experience', Magnetic Resonance in Medical Sciences, vol. 20, no. 3, pp. 320-324. https://doi.org/10.2463/mrms.bc.2020-0069

TY - JOUR

T1 - Myocardial t1-mapping and extracellular volume quantification in patients and putative carriers of muscular dystrophy

T2 - Early experience

AU - Koyanagawa, Kazuhiro

AU - Kobayashi, Yuta

AU - Aikawa, Tadao

AU - Takeda, Atsuhito

AU - Shiraishi, Hideaki

AU - Tsuneta, Satonori

AU - Oyama-Manabe, Noriko

AU - Iwano, Hiroyuki

AU - Nagai, Toshiyuki

AU - Anzai, Toshihisa

PY - 2021

Y1 - 2021

N2 - To assess myocardial fibrosis associated with muscular dystrophy, T1-mapping and extracellular volume fraction (ECV) quantification was prospectively performed using cardiovascular MR (CMR) imaging in 6 male patients with muscular dystrophy and 5 female putative carriers of Duchenne or Becker muscular dys-trophy. Five patients and all putative carriers had an elevated ECV (>29.5% for men and >35.2% for women), suggesting that ECV has a potential to detect diffuse fibrotic changes in patients and putative carriers of muscular dystrophy.

AB - To assess myocardial fibrosis associated with muscular dystrophy, T1-mapping and extracellular volume fraction (ECV) quantification was prospectively performed using cardiovascular MR (CMR) imaging in 6 male patients with muscular dystrophy and 5 female putative carriers of Duchenne or Becker muscular dys-trophy. Five patients and all putative carriers had an elevated ECV (>29.5% for men and >35.2% for women), suggesting that ECV has a potential to detect diffuse fibrotic changes in patients and putative carriers of muscular dystrophy.

KW - Cardiovascular magnetic resonance imaging

KW - Extracellular volume fraction

KW - Muscular dystrophy

KW - Putative carrier

KW - T-mapping

UR - https://www.scopus.com/pages/publications/85114503847

U2 - 10.2463/mrms.bc.2020-0069

DO - 10.2463/mrms.bc.2020-0069

M3 - Article

C2 - 32893256

AN - SCOPUS:85114503847

SN - 1347-3182

VL - 20

SP - 320

EP - 324

JO - Magnetic Resonance in Medical Sciences

JF - Magnetic Resonance in Medical Sciences

IS - 3