Mycobacterium avium-intracellulare-associated colitis in a patient with the acquired immunodeficiency syndrome

A. Wolke, S. Meyers, B. R. Adelsberg, E. J. Bottone, B. Damsker, I. S. Schwartz, H. D. Janowitz

Research output: Contribution to journalArticlepeer-review

30 Scopus citations

Abstract

A 40-year-old bisexual man with the acquired immunodeficiency syndrome developed abdominal pain and bloody diarrhea. At sigmoidoscopy, the mucosa of the rectum and sigmoid colon was edematous, erythematous, and friable, with multiple linear and oval erosions. Histologic examination of rectal biopsies demonstrated innumerable acid-fast bacilli free and within macrophages of the lamina propria. Mycobacterium avium-intracellulare was cultured from the rectal biopsy specimens. Pulmonary tissue and bone marrow cultures also demonstrated this organism. Therapy with several antimycobacterial agents resulted in improvement of symptoms. Among immunocompromised patients the spectrum of enteric pathogens causing colitis should be expanded to include Mycobacterium avium-intracellulare, a potentially treatable organism.

Original languageEnglish
Pages (from-to)225-229
Number of pages5
JournalJournal of Clinical Gastroenterology
Volume6
Issue number3
StatePublished - 1984

Fingerprint

Dive into the research topics of 'Mycobacterium avium-intracellulare-associated colitis in a patient with the acquired immunodeficiency syndrome'. Together they form a unique fingerprint.

Cite this