Mycobacteria and Cryptococci Cultured from the Buffy Coat Of AIDS Patients Prior to Symptomatology: A Rationale for Early Therapy

Beca Damsker, Edward J. Bottone

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Culture of the buffy coat layer of the peripheral blood of 14 AIDS patients demonstrated sustained mycobacteremia or fungemia: ll with Mycobacterium aviumintracellulare, 2 with Cryptococcus neoformans, and one with Mycobacterium tuberculosis. The early detection of these agents prior to the onset of overt symptomatology of disseminated infection due to these microorganisms allowed speculations on an early phase bacteremia and the proposal of prompt inception of antimicrobial therapy while the microbial burden is still manageable. The method also obviates the need for more invasive techniques.

Original languageEnglish
Pages (from-to)343-348
Number of pages6
JournalAIDS Research
Volume2
Issue number4
DOIs
StatePublished - 1986

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