@article{76214689595745eab91857ae3bcd5182,
title = "Mutagenicity of the halogenated olefin, 2 bromo 2 chloro 1, 1 difluoroethylene, a presumed metabolite of the inhalation anesthetic halothane",
abstract = "The presumed halothane metabolite, 2-bromo-2-chloro-1, 1-difluoroethylene, produces both base substitution and frameshift mutations in Salmonella typhimurium. Direct mutagenesis of isolated DNA also was observed by using a Bacillus subtilis transformation assay to score the production of mutagenic lesions in transforming DNA.",
author = "Garro, {A. J.} and Phillips, {R. A.}",
note = "Funding Information: This investigatiown as supportedb y researchg rantsN o. BC-200 from the American Cancer Society and CA22354 from the N.I.H. The authorst hank Ms. V. Lima for her technicaal ssistancaen dthe chemistas t ColumbiaO rganic Chemicalas ndPCR for theirh elpfuld iscussions.",
year = "1977",
doi = "10.1289/ehp.772165",
language = "English",
volume = "Vol. 21",
pages = "65--69",
journal = "Environmental Health Perspectives",
issn = "0091-6765",
publisher = "Public Health Services, US Dept of Health and Human Services",
}