TY - JOUR
T1 - Multiple myeloma in World Trade Center responders
T2 - A case series
AU - Moline, Jacqueline M.
AU - Herbert, Robin
AU - Crowley, Laura
AU - Troy, Kevin
AU - Hodgman, Erica
AU - Shukla, Gauri
AU - Udasin, Iris
AU - Luft, Benjamin
AU - Wallenstein, Sylvan
AU - Landrigan, Philip
AU - Savitz, David A.
N1 - Funding Information:
This work was supported by the Centers for Disease Control and NIOSH, under contract 200-2002-0038 and grants 5U1O 0H008232, U10 OH008225, U10 OH008216, U10 OH008223, U10 OH008239, and U10 OH008275.
PY - 2009/8
Y1 - 2009/8
N2 - OBJECTIVES: We report on cases of multiple myeloma (MM) observed in World Trade Center (WTC) responders registered in the WTC Medical Program. METHODS: Possible cases of MM diagnosed between September 11, 2001, and September 10, 2007, in responders were confirmed if they met the World Health Organization and Mayo Clinic diagnostic criteria. RESULTS: Among 28,252 responders of known sex and age, eight cases of MM were observed (6.8 expected). Four of these cases were observed in responders younger than 45 years at the time of diagnosis (1.2 expected). A slight deficit of MM cases was observed in responders older than 45 years (4 observed, 5.6 expected). CONCLUSION: In this case series, we observe an unusual number of MM cases in WTC responders under 45 years. This finding underscores the importance of maintaining surveillance for cancer and other emerging diseases in this highly exposed population.
AB - OBJECTIVES: We report on cases of multiple myeloma (MM) observed in World Trade Center (WTC) responders registered in the WTC Medical Program. METHODS: Possible cases of MM diagnosed between September 11, 2001, and September 10, 2007, in responders were confirmed if they met the World Health Organization and Mayo Clinic diagnostic criteria. RESULTS: Among 28,252 responders of known sex and age, eight cases of MM were observed (6.8 expected). Four of these cases were observed in responders younger than 45 years at the time of diagnosis (1.2 expected). A slight deficit of MM cases was observed in responders older than 45 years (4 observed, 5.6 expected). CONCLUSION: In this case series, we observe an unusual number of MM cases in WTC responders under 45 years. This finding underscores the importance of maintaining surveillance for cancer and other emerging diseases in this highly exposed population.
UR - http://www.scopus.com/inward/record.url?scp=69549097989&partnerID=8YFLogxK
U2 - 10.1097/JOM.0b013e3181ad49c8
DO - 10.1097/JOM.0b013e3181ad49c8
M3 - Article
C2 - 19620891
AN - SCOPUS:69549097989
SN - 1076-2752
VL - 51
SP - 896
EP - 902
JO - Journal of Occupational and Environmental Medicine
JF - Journal of Occupational and Environmental Medicine
IS - 8
ER -