Multifocal hemorrhagic vasculopathy: Possibly a manifestation of central nervous system vasculitis

Olga Noskin, Richard Libman, Stephan Mayer, Peter Canoll

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

We report a patient with multiple spontaneous intracerebral hemorrhages involving cortical, subcortical, and deep brain structures. Despite extensive evaluation, no etiology was identified, and the possibility of primary central nervous system (CNS) vasculitis was entertained. Brain biopsy revealed small vessels with a lymphocytic infiltrate in brain tissue adjacent to hemorrhage. Despite this nonspecific finding, the patient appeared to respond to immunosuppressive therapy. In this report we review the various presentations of CNS vasculitis and suggest that this diagnosis be considered in the setting of multiple spontaneous intracerebral hemorrhages.

Original languageEnglish
Pages (from-to)43-47
Number of pages5
JournalJournal of Stroke and Cerebrovascular Diseases
Volume15
Issue number1
DOIs
StatePublished - 2006
Externally publishedYes

Keywords

  • Brain biopsy
  • CNS vasculitis
  • Intracerebral hemorrhage

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