Multidimensional en-Face OCT imaging of the retina

  • Richard B. Rosen
  • , Mark Hathaway
  • , John Rogers
  • , Justin Pedro
  • , Patricia Garcia
  • , Philippe Laissue
  • , George M. Dobre
  • , Adrian Gh Podoleanu

Research output: Contribution to journalArticlepeer-review

45 Scopus citations

Abstract

Fast T-scanning (transverse scanning, en-face) was used to build B-scan or C-scan optical coherence tomography (OCT) images of the retina. Several unique signature patterns of en-face (coronal) are reviewed in conjunction with associated confocal images of the fundus and B-scan OCT images. Benefits in combining T-scan OCT with confocal imaging to generate pairs of OCT and confocal images similar to those generated by scanning laser ophthalmoscopy (SLO) are discussed in comparison with the spectral OCT systems. The multichannel potential of the OCT/SLO system is demonstrated with the addition of a third hardware channel which acquires and generates indocyanine green (ICG) fluorescence images. The OCT, confocal SLO and ICG fluorescence images are simultaneously presented in a two or a three screen format. A fourth channel which displays a live mix of frames of the ICG sequence superimposed on the corresponding coronal OCT slices for immediate multidimensional comparison, is also included. OSA ISP software is employed to illustrate the synergy between the simultaneously provided perspectives. This synergy promotes interpretation of information by enhancing diagnostic comparisons and facilitates internal correction of movement artifacts within C-scan and B-scan OCT images using information provided by the SLO channel.

Original languageEnglish
Pages (from-to)4112-4133
Number of pages22
JournalOptics Express
Volume17
Issue number5
DOIs
StatePublished - 2 Mar 2009
Externally publishedYes

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