Multi-protein complexes at the β-globin locus

Milind C. Mahajan; Sherman M. Weissman

doi:10.1093/bfgp/ell001

Multi-protein complexes at the β-globin locus

Milind C. Mahajan, Sherman M. Weissman

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Abstract

Biochemical analysis of the β-globin gene function has led to the identification of several multi-protein complexes at the locus control region (LCR), insulator and promoters. This review briefly summarizes these multi-protein complexes and discusses their contribution towards the regulation of the β-globin gene expression.

Original language	English
Pages (from-to)	62-65
Number of pages	4
Journal	Briefings in Functional Genomics and Proteomics
Volume	5
Issue number	1
DOIs	https://doi.org/10.1093/bfgp/ell001
State	Published - Mar 2006
Externally published	Yes

Keywords

CTCF
EKLF
GATA-1
LCR
MeCP1
NF-E2
SWI/SNF
hnRNP C1/C2
β-globin

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10.1093/bfgp/ell001

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title = "Multi-protein complexes at the β-globin locus",

abstract = "Biochemical analysis of the β-globin gene function has led to the identification of several multi-protein complexes at the locus control region (LCR), insulator and promoters. This review briefly summarizes these multi-protein complexes and discusses their contribution towards the regulation of the β-globin gene expression.",

keywords = "CTCF, EKLF, GATA-1, LCR, MeCP1, NF-E2, SWI/SNF, hnRNP C1/C2, β-globin",

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year = "2006",

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AU - Weissman, Sherman M.

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AB - Biochemical analysis of the β-globin gene function has led to the identification of several multi-protein complexes at the locus control region (LCR), insulator and promoters. This review briefly summarizes these multi-protein complexes and discusses their contribution towards the regulation of the β-globin gene expression.

KW - CTCF

KW - EKLF

KW - GATA-1

KW - LCR

KW - MeCP1

KW - NF-E2

KW - SWI/SNF

KW - hnRNP C1/C2

KW - β-globin

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DO - 10.1093/bfgp/ell001

M3 - Review article

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SN - 1473-9550

VL - 5

SP - 62

EP - 65

JO - Briefings in Functional Genomics and Proteomics

JF - Briefings in Functional Genomics and Proteomics

IS - 1

ER -

Multi-protein complexes at the β-globin locus

Abstract

Keywords

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