TY - JOUR
T1 - Mucin-associated sialosyl-Tn antigen expression in gastric cancer correlates with an adverse outcome
AU - Werther, J. L.
AU - Rivera-MacMurray, S.
AU - Bruckner, H.
AU - Tatematsu, M.
AU - Itzkowitz, S. H.
PY - 1994/3
Y1 - 1994/3
N2 - The expression of sialosyl-Tn (STn) antigen was evaluated by immunohistochemistry in primary gastric cancers. Twenty-one of 31 (68%) gastric cancers expressed STn, regardless of tumour location, stage or histological type. Eighty-one per cent of patients with STn-positive tumours died of their disease or had recurrent cancer, compared with 20% of patients with STn-negative tumours (P < 0.002). STn may be a useful prognostic marker in patients with gastric cancer.
AB - The expression of sialosyl-Tn (STn) antigen was evaluated by immunohistochemistry in primary gastric cancers. Twenty-one of 31 (68%) gastric cancers expressed STn, regardless of tumour location, stage or histological type. Eighty-one per cent of patients with STn-positive tumours died of their disease or had recurrent cancer, compared with 20% of patients with STn-negative tumours (P < 0.002). STn may be a useful prognostic marker in patients with gastric cancer.
UR - http://www.scopus.com/inward/record.url?scp=0028297373&partnerID=8YFLogxK
U2 - 10.1038/bjc.1994.114
DO - 10.1038/bjc.1994.114
M3 - Article
C2 - 8123499
AN - SCOPUS:0028297373
SN - 0007-0920
VL - 69
SP - 613
EP - 616
JO - British Journal of Cancer
JF - British Journal of Cancer
IS - 3
ER -