MRI of malignant fibrous histiocytoma of soft tissue: analysis of 13 cases with pathologic correlation

Theodore T. Miller; George Hermann; I. Fikry Abdelwahab; Michael J. Klein; Samuel Kenan; Michael M. Lewis

doi:10.1007/BF02412360

MRI of malignant fibrous histiocytoma of soft tissue: analysis of 13 cases with pathologic correlation

Theodore T. Miller
, George Hermann
, I. Fikry Abdelwahab
, Michael J. Klein
, Samuel Kenan
, Michael M. Lewis

Icahn School of Medicine at Mount Sinai

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

We reviewed the magnetic resonance (MR) appearances of 13 malignant fibrous histiocytomas (MFH) of soft tissue and correlated each with the respective lesion's histopathology. The MR images were evaluated for signal intensity on T1- and T2-weighted spin echo sequences, homogeneity of the lesion, presence of internal low signal septations, and margin definition. Histologic subtypes of MFH included storiform-pleomorphic, giant cell, myxoid, and inflammatory. We could not establish a correlation between MR appearance and histopathology. Instead, our series exhibited general features suggestive of malignant soft tissue neoplasms, namely poor margin definition, internal low signal septation, and heterogeneous high signal intensity on T2-weighted images.

Original language	English
Pages (from-to)	271-275
Number of pages	5
Journal	Skeletal Radiology
Volume	23
Issue number	4
DOIs	https://doi.org/10.1007/BF02412360
State	Published - May 1994

Keywords

Magnetic resonance imaging
Malignant fibrous histiocytoma
Pathology
Soft tissue tumors

Access to Document

10.1007/BF02412360

Cite this

@article{b04f67f46db74b9b815e0fa3bd13895b,

title = "MRI of malignant fibrous histiocytoma of soft tissue: analysis of 13 cases with pathologic correlation",

abstract = "We reviewed the magnetic resonance (MR) appearances of 13 malignant fibrous histiocytomas (MFH) of soft tissue and correlated each with the respective lesion's histopathology. The MR images were evaluated for signal intensity on T1- and T2-weighted spin echo sequences, homogeneity of the lesion, presence of internal low signal septations, and margin definition. Histologic subtypes of MFH included storiform-pleomorphic, giant cell, myxoid, and inflammatory. We could not establish a correlation between MR appearance and histopathology. Instead, our series exhibited general features suggestive of malignant soft tissue neoplasms, namely poor margin definition, internal low signal septation, and heterogeneous high signal intensity on T2-weighted images.",

keywords = "Magnetic resonance imaging, Malignant fibrous histiocytoma, Pathology, Soft tissue tumors",

author = "Miller, \{Theodore T.\} and George Hermann and Abdelwahab, \{I. Fikry\} and Klein, \{Michael J.\} and Samuel Kenan and Lewis, \{Michael M.\}",

year = "1994",

month = may,

doi = "10.1007/BF02412360",

language = "English",

volume = "23",

pages = "271--275",

journal = "Skeletal Radiology",

issn = "0364-2348",

publisher = "Springer Science and Business Media Deutschland GmbH",

number = "4",

}

TY - JOUR

T1 - MRI of malignant fibrous histiocytoma of soft tissue

T2 - analysis of 13 cases with pathologic correlation

AU - Miller, Theodore T.

AU - Hermann, George

AU - Abdelwahab, I. Fikry

AU - Klein, Michael J.

AU - Kenan, Samuel

AU - Lewis, Michael M.

PY - 1994/5

Y1 - 1994/5

N2 - We reviewed the magnetic resonance (MR) appearances of 13 malignant fibrous histiocytomas (MFH) of soft tissue and correlated each with the respective lesion's histopathology. The MR images were evaluated for signal intensity on T1- and T2-weighted spin echo sequences, homogeneity of the lesion, presence of internal low signal septations, and margin definition. Histologic subtypes of MFH included storiform-pleomorphic, giant cell, myxoid, and inflammatory. We could not establish a correlation between MR appearance and histopathology. Instead, our series exhibited general features suggestive of malignant soft tissue neoplasms, namely poor margin definition, internal low signal septation, and heterogeneous high signal intensity on T2-weighted images.

AB - We reviewed the magnetic resonance (MR) appearances of 13 malignant fibrous histiocytomas (MFH) of soft tissue and correlated each with the respective lesion's histopathology. The MR images were evaluated for signal intensity on T1- and T2-weighted spin echo sequences, homogeneity of the lesion, presence of internal low signal septations, and margin definition. Histologic subtypes of MFH included storiform-pleomorphic, giant cell, myxoid, and inflammatory. We could not establish a correlation between MR appearance and histopathology. Instead, our series exhibited general features suggestive of malignant soft tissue neoplasms, namely poor margin definition, internal low signal septation, and heterogeneous high signal intensity on T2-weighted images.

KW - Magnetic resonance imaging

KW - Malignant fibrous histiocytoma

KW - Pathology

KW - Soft tissue tumors

UR - https://www.scopus.com/pages/publications/0028277794

U2 - 10.1007/BF02412360

DO - 10.1007/BF02412360

M3 - Article

C2 - 8059252

AN - SCOPUS:0028277794

SN - 0364-2348

VL - 23

SP - 271

EP - 275

JO - Skeletal Radiology

JF - Skeletal Radiology

IS - 4

ER -

MRI of malignant fibrous histiocytoma of soft tissue: analysis of 13 cases with pathologic correlation

Abstract

Keywords

Access to Document

Fingerprint

Cite this