MRI negative myelopathy post mild SARS-CoV-2 infection: vasculopathy or inflammatory myelitis?

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6 Scopus citations

Abstract

Since the onset of the COVID-19 pandemic, there have been rare reports of spinal cord pathology diagnosed as inflammatory myelopathy and suspected spinal cord ischemia after SARS-CoV-2 infection. Herein, we report five cases of clinical myelopathy and myeloradiculopathy in the setting of post-COVID-19 disease, which were all radiographically negative. Unlike prior reports which typically characterized hospitalized patients with severe COVID-19 disease and critical illness, these patients typically had asymptomatic or mild-moderate COVID-19 disease and lacked radiologic evidence of structural spinal cord abnormality. This case series highlights that COVID-19 associated myelopathy is not rare, requires a high degree of clinical suspicion as imaging markers may be negative, and raises several possible pathophysiologic mechanisms.

Original languageEnglish
Pages (from-to)650-655
Number of pages6
JournalJournal of NeuroVirology
Volume27
Issue number4
DOIs
StatePublished - Aug 2021

Keywords

  • Inflammatory myelopathy
  • Ischemic myelopathy
  • Long Haul Covid
  • Post Acute Covid-19 Syndrome
  • Transverse myelopathy syndrome

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