Movement disorders and AIDS: A review

Winona Tse, Maria G. Cersosimo, Jean Michel Gracies, Susan Morgello, C. Warren Olanow, William Koller

Research output: Contribution to journalReview articlepeer-review

93 Scopus citations


Movement disorders are a potential neurologic complication of acquired immune deficiency syndrome (AIDS), and may sometimes represent the initial manifestation of HIV infection. Dopaminergic dysfunction and the predilection of HIV infection to affect subcortical structures are thought to underlie the development of movement disorders such as parkinsonism in AIDS patients. In this review, we will discuss the clinical presentations, etiology and treatment of the various AIDS-related hypokinetic and hyperkinetic movement disorders, such as parkinsonism, chorea, myoclonus and dystonia. This review will also summarize current concepts regarding the pathophysiology of parkinsonism in HIV infection.

Original languageEnglish
Pages (from-to)323-334
Number of pages12
JournalParkinsonism and Related Disorders
Issue number6
StatePublished - Aug 2004


  • AIDS
  • Chorea
  • Dopamine
  • Human immunodeficiency virus
  • Movement disorders
  • Parkinsonism


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