Movement disorders and AIDS: A review

Winona Tse; Maria G. Cersosimo; Jean Michel Gracies; Susan Morgello; C. Warren Olanow; William Koller

doi:10.1016/j.parkreldis.2004.03.001

Movement disorders and AIDS: A review

Winona Tse, Maria G. Cersosimo, Jean Michel Gracies, Susan Morgello, C. Warren Olanow, William Koller

Research output: Contribution to journal › Review article › peer-review

96 Scopus citations

Abstract

Movement disorders are a potential neurologic complication of acquired immune deficiency syndrome (AIDS), and may sometimes represent the initial manifestation of HIV infection. Dopaminergic dysfunction and the predilection of HIV infection to affect subcortical structures are thought to underlie the development of movement disorders such as parkinsonism in AIDS patients. In this review, we will discuss the clinical presentations, etiology and treatment of the various AIDS-related hypokinetic and hyperkinetic movement disorders, such as parkinsonism, chorea, myoclonus and dystonia. This review will also summarize current concepts regarding the pathophysiology of parkinsonism in HIV infection.

Original language	English
Pages (from-to)	323-334
Number of pages	12
Journal	Parkinsonism and Related Disorders
Volume	10
Issue number	6
DOIs	https://doi.org/10.1016/j.parkreldis.2004.03.001
State	Published - Aug 2004

Keywords

AIDS
Chorea
Dopamine
Human immunodeficiency virus
Movement disorders
Parkinsonism

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10.1016/j.parkreldis.2004.03.001

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title = "Movement disorders and AIDS: A review",

abstract = "Movement disorders are a potential neurologic complication of acquired immune deficiency syndrome (AIDS), and may sometimes represent the initial manifestation of HIV infection. Dopaminergic dysfunction and the predilection of HIV infection to affect subcortical structures are thought to underlie the development of movement disorders such as parkinsonism in AIDS patients. In this review, we will discuss the clinical presentations, etiology and treatment of the various AIDS-related hypokinetic and hyperkinetic movement disorders, such as parkinsonism, chorea, myoclonus and dystonia. This review will also summarize current concepts regarding the pathophysiology of parkinsonism in HIV infection.",

keywords = "AIDS, Chorea, Dopamine, Human immunodeficiency virus, Movement disorders, Parkinsonism",

author = "Winona Tse and Cersosimo, {Maria G.} and Gracies, {Jean Michel} and Susan Morgello and Olanow, {C. Warren} and William Koller",

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T2 - A review

AU - Tse, Winona

AU - Cersosimo, Maria G.

AU - Gracies, Jean Michel

AU - Morgello, Susan

AU - Olanow, C. Warren

AU - Koller, William

PY - 2004/8

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N2 - Movement disorders are a potential neurologic complication of acquired immune deficiency syndrome (AIDS), and may sometimes represent the initial manifestation of HIV infection. Dopaminergic dysfunction and the predilection of HIV infection to affect subcortical structures are thought to underlie the development of movement disorders such as parkinsonism in AIDS patients. In this review, we will discuss the clinical presentations, etiology and treatment of the various AIDS-related hypokinetic and hyperkinetic movement disorders, such as parkinsonism, chorea, myoclonus and dystonia. This review will also summarize current concepts regarding the pathophysiology of parkinsonism in HIV infection.

AB - Movement disorders are a potential neurologic complication of acquired immune deficiency syndrome (AIDS), and may sometimes represent the initial manifestation of HIV infection. Dopaminergic dysfunction and the predilection of HIV infection to affect subcortical structures are thought to underlie the development of movement disorders such as parkinsonism in AIDS patients. In this review, we will discuss the clinical presentations, etiology and treatment of the various AIDS-related hypokinetic and hyperkinetic movement disorders, such as parkinsonism, chorea, myoclonus and dystonia. This review will also summarize current concepts regarding the pathophysiology of parkinsonism in HIV infection.

KW - AIDS

KW - Chorea

KW - Dopamine

KW - Human immunodeficiency virus

KW - Movement disorders

KW - Parkinsonism

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VL - 10

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JO - Parkinsonism and Related Disorders

JF - Parkinsonism and Related Disorders

IS - 6

ER -

Movement disorders and AIDS: A review

Abstract

Keywords

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