Abstract
Revertant clones of murine sarcoma virus transformed nonproducer BALB/3T3 cells have been isolated by selection of iododeoxyuridine-resistant colonies in methylcellulose. Each revertant contained a rescuable sarcoma virus but demonstrated both in vitro and in vivo biologic properties of nontransformed BALB/3T3 cells. Further, each clone was highly susceptible to retransformation by added sarcoma virus. The evidence indicates that these lines comprise a new class of morphologic revertants of murine sarcoma virus transformed cells.
Original language | English |
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Pages (from-to) | 339-346 |
Number of pages | 8 |
Journal | Virology |
Volume | 57 |
Issue number | 2 |
DOIs | |
State | Published - Feb 1974 |
Externally published | Yes |