Monocytes and dendritic cells in injury and regeneration

Elise N. Erman; Meryl C. Nath; Matthew D. Cheung; Anupam Agarwal; James F. George

doi:10.1016/B978-0-12-823318-4.00017-2

Monocytes and dendritic cells in injury and regeneration

Elise N. Erman, Meryl C. Nath, Matthew D. Cheung, Anupam Agarwal, James F. George

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Myeloid cell populations play critical roles in the context of acute kidney injury and recovery. This chapter provides a description of acute kidney injury and an explanation of the various model systems used to study the mononuclear phagocyte system, with a focus on ischemia-reperfusion injury. The role of cellular damage caused by the initial insult and function of infiltrating versus resident cell populations through injury and recovery, or if there is a failure to restore homeostasis, are discussed.

Original language	English
Title of host publication	Regenerative Nephrology
Publisher	Elsevier
Pages	93-102
Number of pages	10
ISBN (Electronic)	9780128233184
DOIs	https://doi.org/10.1016/B978-0-12-823318-4.00017-2
State	Published - 1 Jan 2021
Externally published	Yes

Keywords

Acute kidney injury
Dendritic cells
Inflammation
Ischemia reperfusion
Macrophages
Monocytes
Recovery
Regeneration

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10.1016/B978-0-12-823318-4.00017-2

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AU - Erman, Elise N.

AU - Nath, Meryl C.

AU - Cheung, Matthew D.

AU - Agarwal, Anupam

AU - George, James F.

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AB - Myeloid cell populations play critical roles in the context of acute kidney injury and recovery. This chapter provides a description of acute kidney injury and an explanation of the various model systems used to study the mononuclear phagocyte system, with a focus on ischemia-reperfusion injury. The role of cellular damage caused by the initial insult and function of infiltrating versus resident cell populations through injury and recovery, or if there is a failure to restore homeostasis, are discussed.

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KW - Dendritic cells

KW - Inflammation

KW - Ischemia reperfusion

KW - Macrophages

KW - Monocytes

KW - Recovery

KW - Regeneration

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EP - 102

BT - Regenerative Nephrology

PB - Elsevier

ER -

Monocytes and dendritic cells in injury and regeneration

Abstract

Keywords

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