Monoamine oxidase and cigarette smoking

Joanna S. Fowler; Jean Logan; Gene Jack Wang; Nora D. Volkow

doi:10.1016/S0161-813X(02)00109-2

Monoamine oxidase and cigarette smoking

Joanna S. Fowler, Jean Logan, Gene Jack Wang, Nora D. Volkow

Research output: Contribution to journal › Article › peer-review

206 Scopus citations

Abstract

Current cigarette smokers have reduced monoamine oxidase (MAO) and there is evidence that this is a pharmacological effect of tobacco smoke exposure rather than a biological characteristic of smokers. This article summarizes human and animal studies documenting the inhibitory effects of tobacco smoke on MAO and discusses MAO inhibition in the context of smoking epidemiology, MAO inhibitor compounds in tobacco, reinvestigations of low platelet MAO in psychiatric disorders and smoking cessation.

Original language	English
Pages (from-to)	75-82
Number of pages	8
Journal	NeuroToxicology
Volume	24
Issue number	1
DOIs	https://doi.org/10.1016/S0161-813X(02)00109-2
State	Published - Jan 2003
Externally published	Yes

Keywords

Cigarette smoking
Monoamine oxidase
Positron emission tomography
Smoking cessation
Smoking epidemiology
Tobacco

Access to Document

10.1016/S0161-813X(02)00109-2

Cite this

@article{6e455ebd26884449ba4c06e0444539b7,

title = "Monoamine oxidase and cigarette smoking",

abstract = "Current cigarette smokers have reduced monoamine oxidase (MAO) and there is evidence that this is a pharmacological effect of tobacco smoke exposure rather than a biological characteristic of smokers. This article summarizes human and animal studies documenting the inhibitory effects of tobacco smoke on MAO and discusses MAO inhibition in the context of smoking epidemiology, MAO inhibitor compounds in tobacco, reinvestigations of low platelet MAO in psychiatric disorders and smoking cessation.",

keywords = "Cigarette smoking, Monoamine oxidase, Positron emission tomography, Smoking cessation, Smoking epidemiology, Tobacco",

author = "Fowler, {Joanna S.} and Jean Logan and Wang, {Gene Jack} and Volkow, {Nora D.}",

note = "Funding Information: This work was carried out at Brookhaven National Laboratory under contract DE-AC02-98CH10886 with the US Department of Energy and supported by its Office of Health and Environmental Research and by the National Institutes of Health (National Institute of Neurological Disease and Stroke and National Institute on Drug Abuse).",

year = "2003",

month = jan,

doi = "10.1016/S0161-813X(02)00109-2",

language = "English",

volume = "24",

pages = "75--82",

journal = "NeuroToxicology",

issn = "0161-813X",

publisher = "Elsevier",

number = "1",

}

TY - JOUR

T1 - Monoamine oxidase and cigarette smoking

AU - Fowler, Joanna S.

AU - Logan, Jean

AU - Wang, Gene Jack

AU - Volkow, Nora D.

N1 - Funding Information: This work was carried out at Brookhaven National Laboratory under contract DE-AC02-98CH10886 with the US Department of Energy and supported by its Office of Health and Environmental Research and by the National Institutes of Health (National Institute of Neurological Disease and Stroke and National Institute on Drug Abuse).

PY - 2003/1

Y1 - 2003/1

N2 - Current cigarette smokers have reduced monoamine oxidase (MAO) and there is evidence that this is a pharmacological effect of tobacco smoke exposure rather than a biological characteristic of smokers. This article summarizes human and animal studies documenting the inhibitory effects of tobacco smoke on MAO and discusses MAO inhibition in the context of smoking epidemiology, MAO inhibitor compounds in tobacco, reinvestigations of low platelet MAO in psychiatric disorders and smoking cessation.

AB - Current cigarette smokers have reduced monoamine oxidase (MAO) and there is evidence that this is a pharmacological effect of tobacco smoke exposure rather than a biological characteristic of smokers. This article summarizes human and animal studies documenting the inhibitory effects of tobacco smoke on MAO and discusses MAO inhibition in the context of smoking epidemiology, MAO inhibitor compounds in tobacco, reinvestigations of low platelet MAO in psychiatric disorders and smoking cessation.

KW - Cigarette smoking

KW - Monoamine oxidase

KW - Positron emission tomography

KW - Smoking cessation

KW - Smoking epidemiology

KW - Tobacco

UR - http://www.scopus.com/inward/record.url?scp=0037231224&partnerID=8YFLogxK

U2 - 10.1016/S0161-813X(02)00109-2

DO - 10.1016/S0161-813X(02)00109-2

M3 - Article

C2 - 12564384

AN - SCOPUS:0037231224

SN - 0161-813X

VL - 24

SP - 75

EP - 82

JO - NeuroToxicology

JF - NeuroToxicology

IS - 1

ER -

Monoamine oxidase and cigarette smoking

Abstract

Keywords

Access to Document

Fingerprint

Cite this