TY - JOUR
T1 - Monitoring glycemic control
T2 - The cornerstone ofdiabetes care
AU - LeRoith, Derek
AU - Smith, Deirdre O.
N1 - Funding Information:
This article was supported by an educational grant from Aventis Pharmaceuticals Inc., Bridgewater, New Jersey.
PY - 2005/10
Y1 - 2005/10
N2 - Background: Diabetes mellitus is associated with1026 significant morbidity and mortality and escalating costs, and its prevalence is increasing to epidemic proportions. Studies have consistently documented the importance of glycemic control in delaying the onset and decreasing the incidence of both the short- and long-term complications of diabetes. Although glycemic control is difficult to achieve and challenging to maintain, its impact on disease outcomes is well worth the effort. Objective: This article reviews the importance of 1026 monitoring and tightly controlling blood glucose concentrations in patients with diabetes and the methods and tools available for achieving these goals. Methods: This clinical review was developed using 102 a MEDLINE search of the literature from 1990 to 2005 using the terms diabetes, glucose control, glucose monitoring, A1c, and hypoglycemia. Results: The complications of diabetes can be prevented 1026 or sharply curtailed through tight glycemic control, which requires frequent monitoring of blood glucose levels, careful attention to diet and exercise, and the use of medications. The progressive nature of diabetes imposes the need for frequent and regular monitoring, leading to data-driven adjustments to therapy to maintain optimal glucose levels. Failure to achieve glycemic control is often the result of a failure to educate the patient about how to monitor blood glucose levels and the importance of accuracy in doing so. Conclusions: Tight glycemic control requires an 102 educated and motivated patient, an appropriate treatment regimen, vigilant monitoring, and a close partnership between the patient and a multidisciplinary team of health care professionals to ensure accurate monitoring and appropriate actions. The growing array of monitoring devices contributes to this effort by providing increased convenience and accuracy.
AB - Background: Diabetes mellitus is associated with1026 significant morbidity and mortality and escalating costs, and its prevalence is increasing to epidemic proportions. Studies have consistently documented the importance of glycemic control in delaying the onset and decreasing the incidence of both the short- and long-term complications of diabetes. Although glycemic control is difficult to achieve and challenging to maintain, its impact on disease outcomes is well worth the effort. Objective: This article reviews the importance of 1026 monitoring and tightly controlling blood glucose concentrations in patients with diabetes and the methods and tools available for achieving these goals. Methods: This clinical review was developed using 102 a MEDLINE search of the literature from 1990 to 2005 using the terms diabetes, glucose control, glucose monitoring, A1c, and hypoglycemia. Results: The complications of diabetes can be prevented 1026 or sharply curtailed through tight glycemic control, which requires frequent monitoring of blood glucose levels, careful attention to diet and exercise, and the use of medications. The progressive nature of diabetes imposes the need for frequent and regular monitoring, leading to data-driven adjustments to therapy to maintain optimal glucose levels. Failure to achieve glycemic control is often the result of a failure to educate the patient about how to monitor blood glucose levels and the importance of accuracy in doing so. Conclusions: Tight glycemic control requires an 102 educated and motivated patient, an appropriate treatment regimen, vigilant monitoring, and a close partnership between the patient and a multidisciplinary team of health care professionals to ensure accurate monitoring and appropriate actions. The growing array of monitoring devices contributes to this effort by providing increased convenience and accuracy.
KW - Blood glucose self-monitoring
KW - Diabetes mellitus
KW - Glycemic control
KW - Glycosylated hemoglobin
KW - Hypoglycemia
KW - Monitoring devices
UR - http://www.scopus.com/inward/record.url?scp=28444489240&partnerID=8YFLogxK
U2 - 10.1016/j.clinthera.2005.10.010
DO - 10.1016/j.clinthera.2005.10.010
M3 - Article
AN - SCOPUS:28444489240
SN - 0149-2918
VL - 27
SP - 1489
EP - 1499
JO - Clinical Therapeutics
JF - Clinical Therapeutics
IS - 10
ER -