Molecular cloning of an oncogenic replication-component virus that causes lymphoproliferative disease in turkeys

E. Gak, A. Yaniv, A. Chajut, M. Ianconescu, S. R. Tronick, A. Gazit

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

The lymphoproliferative disease virus of turkeys was molecularly cloned, structurally mapped, and shown to represent a distinct class of retroviruses evolutionarily related to the avian leukemia-sarcoma virus group. The cloned provirus did not contain any known oncogene or other cellularly derived sequences and was established as a replication-competent oncogenic entity capable of inducing the disease in the absence of any associated transforming counterpart.

Original languageEnglish
Pages (from-to)2877-2880
Number of pages4
JournalJournal of Virology
Volume63
Issue number6
DOIs
StatePublished - 1989
Externally publishedYes

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