Modulation of myosin phosphorylation rates by weak near ambient DC magnetic fields

M. S. Markov; J. T. Ryaby; S. Wang; A. A. Pilla

doi:10.1109/NEBC.1992.285957

Modulation of myosin phosphorylation rates by weak near ambient DC magnetic fields

M. S. Markov, J. T. Ryaby, S. Wang, A. A. Pilla

Icahn School of Medicine at Mount Sinai

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

3 Scopus citations

Abstract

The present study was designed to evaluate the effect of weak, environmental range, AC and DC magnetic fields on myosin light chain phosphorylation in a cell-free system. The exposure system applied AC (16 Hz, 20.9 mu T) and DC (0-200 mu T, vertically and/or horizontally) magnetic fields. The results suggest that all of the AC, DC, and combination AC/DC magnetic fields significantly (30-100%, p<.01) affect myosin phosphorylation. The most surprising and important finding shows that only DC field variations are sufficient to raise or lower the rate of phosphorylation. When mu-metal shielding was employed, phosphorylation decreased to 35% of the control value. Phosphorylation kinetics were also modified by these fields.

Original language	English
Title of host publication	Proceedings of the 18th IEEE Annual Northeast Bioengineering Conference, NEBEC 1992
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	63-64
Number of pages	2
ISBN (Electronic)	0780309022
DOIs	https://doi.org/10.1109/NEBC.1992.285957
State	Published - 1992
Event	18th IEEE Annual Northeast Bioengineering Conference, NEBEC 1992 - Kingston, United States Duration: 12 Mar 1992 → 13 Mar 1992

Publication series

Name	Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC
ISSN (Print)	1071-121X
ISSN (Electronic)	2160-7001

Conference

Conference	18th IEEE Annual Northeast Bioengineering Conference, NEBEC 1992
Country/Territory	United States
City	Kingston
Period	12/03/92 → 13/03/92

Access to Document

10.1109/NEBC.1992.285957

Cite this

Markov, M. S., Ryaby, J. T., Wang, S., & Pilla, A. A. (1992). Modulation of myosin phosphorylation rates by weak near ambient DC magnetic fields. In Proceedings of the 18th IEEE Annual Northeast Bioengineering Conference, NEBEC 1992 (pp. 63-64). Article 285957 (Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/NEBC.1992.285957

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title = "Modulation of myosin phosphorylation rates by weak near ambient DC magnetic fields",

abstract = "The present study was designed to evaluate the effect of weak, environmental range, AC and DC magnetic fields on myosin light chain phosphorylation in a cell-free system. The exposure system applied AC (16 Hz, 20.9 mu T) and DC (0-200 mu T, vertically and/or horizontally) magnetic fields. The results suggest that all of the AC, DC, and combination AC/DC magnetic fields significantly (30-100%, p<.01) affect myosin phosphorylation. The most surprising and important finding shows that only DC field variations are sufficient to raise or lower the rate of phosphorylation. When mu-metal shielding was employed, phosphorylation decreased to 35% of the control value. Phosphorylation kinetics were also modified by these fields.",

author = "Markov, {M. S.} and Ryaby, {J. T.} and S. Wang and Pilla, {A. A.}",

note = "Publisher Copyright: {\textcopyright} 1992 IEEE.; 18th IEEE Annual Northeast Bioengineering Conference, NEBEC 1992 ; Conference date: 12-03-1992 Through 13-03-1992",

year = "1992",

doi = "10.1109/NEBC.1992.285957",

language = "English",

series = "Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

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address = "United States",

}

Markov, MS, Ryaby, JT, Wang, S & Pilla, AA 1992, Modulation of myosin phosphorylation rates by weak near ambient DC magnetic fields. in Proceedings of the 18th IEEE Annual Northeast Bioengineering Conference, NEBEC 1992., 285957, Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC, Institute of Electrical and Electronics Engineers Inc., pp. 63-64, 18th IEEE Annual Northeast Bioengineering Conference, NEBEC 1992, Kingston, United States, 12/03/92. https://doi.org/10.1109/NEBC.1992.285957

Modulation of myosin phosphorylation rates by weak near ambient DC magnetic fields. / Markov, M. S.; Ryaby, J. T.; Wang, S. et al.
Proceedings of the 18th IEEE Annual Northeast Bioengineering Conference, NEBEC 1992. Institute of Electrical and Electronics Engineers Inc., 1992. p. 63-64 285957 (Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Modulation of myosin phosphorylation rates by weak near ambient DC magnetic fields

AU - Markov, M. S.

AU - Ryaby, J. T.

AU - Wang, S.

AU - Pilla, A. A.

PY - 1992

Y1 - 1992

N2 - The present study was designed to evaluate the effect of weak, environmental range, AC and DC magnetic fields on myosin light chain phosphorylation in a cell-free system. The exposure system applied AC (16 Hz, 20.9 mu T) and DC (0-200 mu T, vertically and/or horizontally) magnetic fields. The results suggest that all of the AC, DC, and combination AC/DC magnetic fields significantly (30-100%, p<.01) affect myosin phosphorylation. The most surprising and important finding shows that only DC field variations are sufficient to raise or lower the rate of phosphorylation. When mu-metal shielding was employed, phosphorylation decreased to 35% of the control value. Phosphorylation kinetics were also modified by these fields.

AB - The present study was designed to evaluate the effect of weak, environmental range, AC and DC magnetic fields on myosin light chain phosphorylation in a cell-free system. The exposure system applied AC (16 Hz, 20.9 mu T) and DC (0-200 mu T, vertically and/or horizontally) magnetic fields. The results suggest that all of the AC, DC, and combination AC/DC magnetic fields significantly (30-100%, p<.01) affect myosin phosphorylation. The most surprising and important finding shows that only DC field variations are sufficient to raise or lower the rate of phosphorylation. When mu-metal shielding was employed, phosphorylation decreased to 35% of the control value. Phosphorylation kinetics were also modified by these fields.

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M3 - Conference contribution

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BT - Proceedings of the 18th IEEE Annual Northeast Bioengineering Conference, NEBEC 1992

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 18th IEEE Annual Northeast Bioengineering Conference, NEBEC 1992

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Markov MS, Ryaby JT, Wang S, Pilla AA. Modulation of myosin phosphorylation rates by weak near ambient DC magnetic fields. In Proceedings of the 18th IEEE Annual Northeast Bioengineering Conference, NEBEC 1992. Institute of Electrical and Electronics Engineers Inc. 1992. p. 63-64. 285957. (Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC). doi: 10.1109/NEBC.1992.285957

Modulation of myosin phosphorylation rates by weak near ambient DC magnetic fields

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