Modulating Mineralocorticoid Receptor with Non-steroidal Antagonists. New Opportunities for the Development of Potent and Selective Ligands without Off-Target Side Effects

Keyphrases

• Non-steroidal 100%
• Mineralocorticoid Receptor Antagonists 100%
• Mineralocorticoid Receptor 100%
• Selective Ligands 100%
• Non-steroidal Ligands 100%
• Diabetic Nephropathy 50%
• Hypertension 50%
• Congestive Heart Failure 50%
• Active Sites 50%
• Human Disease 50%
• Structure-activity Relationship 50%
• Therapeutic Effect 50%
• Ligand-binding Domain 50%
• Physical Properties 50%
• Chemical Scaffolds 50%
• Process Optimization 50%
• Chemical Synthesis 50%
• Steroidal 50%
• Pharmaceutical Companies 50%
• Unwanted Side Effects 50%
• Complex Chemicals 50%
• Academic Groups 50%
• Coregulators 50%
• Challenging Issues 50%
• Groups of Companies 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Mineralocorticoid Receptor 100%
• Mineralocorticoid Antagonist 100%
• Side Effect 100%
• Congestive Heart Failure 50%
• Receptor 50%
• Clinical Study 50%
• Structure Activity Relationship 50%
• Therapeutic Effect 50%
• Diabetic Nephropathy 50%
• Diseases 50%