Modifying systemic responses with anesthetic techniques

C. Weissman, I. Hollinger

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Anesthetic agents and techniques can modify the systemic responses to surgical injury. Epidural blockade with local anesthetics in patients undergoing lower abdominal or lower extremity surgery can markedly attenuate the plasma levels of many of the stress hormones. It appears that it is more difficult to achieve comparable degrees of attenuation in upper abdominal surgery. Whether such techniques can be used in patients with multiple system organ failure to attenuate the autocatabolic processes is unclear.

Original languageEnglish
Pages (from-to)221-235
Number of pages15
JournalAnesthesiology Clinics of North America
Issue number1
StatePublished - 1988
Externally publishedYes


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