Abstract
Proper injection of poly-L-lactic acid has a role in avoiding development of subcutaneous papules. We evaluated the safety and efficacy of our injection technique ("cross-fanning") and compared it to 4 previous studies. Forty patients were evaluated for adverse events (bruising, edema, erythema, subcutaneous papules) and satisfaction. Papule incidence was compared with the other studies. The incidence of papules (4/40) was significantly lower than that of VEGA and Chelsea and Westminster (P = 0.00003, P = 0.03), but not significantly different than APEX002 or Blue Pacific (P = 0.42, P = 0.61). Bruising (5/40), edema (2/40), papules (4/40), and patient self-satisfaction (80%, P = 0.0001) was also documented. We maintain that cross-fanning has an excellent safety profile and patient satisfaction rate. We also maintain that our modified technique has advantages over the recommended "tunneling cross-hatch" and "depot" technique. Because 38 of 40 patients were HIV-negative, this study also represents the first single-practice series of proper injection of poly-L-lactic acid administration in the immuno-competent patient.
Original language | English |
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Pages (from-to) | 435-441 |
Number of pages | 7 |
Journal | Annals of Plastic Surgery |
Volume | 64 |
Issue number | 4 |
DOIs | |
State | Published - Apr 2010 |
Externally published | Yes |
Keywords
- Cross-fanning
- Cross-tunneling
- Granuloma
- HIV
- Injection technique
- Lipoatrophy
- Poly-L-lactic acid
- Sculptra
- Subcutaneous papules